A direct and selective electrochemical hydrogen sulfide sensor.
Anal Chim Acta
; 1045: 67-76, 2019 Jan 03.
Article
en En
| MEDLINE
| ID: mdl-30454574
Continuous, in situ detection of hydrogen sulfide (H2S) in biological milieu is made possible with electrochemical methods, but direct amperometry is constrained by the generation of elemental sulfur as an oxidative byproduct. Deposition of a sulfur layer passivates the working electrode, reducing sensitivity and causing performance variability. Herein, we report on the use of a surface preconditioning procedure to deposit elemental sulfur on a glassy carbon electrode prior to measurement and evaluate performance with common analytical metrics. The lack of traditional anti-poisoning techniques (e.g. redox mediators, cleaning pulses) also allowed for facile surface modification with electropolymerized films. For the first time, a series of electropolymerized films were characterized for their H2S permselective behavior against common biological interferents. Highly selective, film-modified electrodes were then evaluated for their anti-biofouling ability in simulated wound fluid. The final optimized electrode was capable of measuring H2S with a low detection limit (i.e., <100â¯nM) and â¼80% of its initial sensitivity in proteinaceous media.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Técnicas Electroquímicas
/
Sulfuro de Hidrógeno
Idioma:
En
Revista:
Anal Chim Acta
Año:
2019
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Países Bajos