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Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity.
Walsh, Scott R; Bastin, Donald; Chen, Lan; Nguyen, Andrew; Storbeck, Christopher J; Lefebvre, Charles; Stojdl, David; Bramson, Jonathan L; Bell, John C; Wan, Yonghong.
Afiliación
  • Walsh SR; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Bastin D; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Chen L; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Nguyen A; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Storbeck CJ; Centre for Innovative Cancer Research, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
  • Lefebvre C; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
  • Stojdl D; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
  • Bramson JL; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
  • Bell JC; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
  • Wan Y; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
J Clin Invest ; 129(2): 518-530, 2019 02 01.
Article en En | MEDLINE | ID: mdl-30422820
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Melanoma Experimental / Transducción de Señal / Interferón beta / Interferón-alfa / Traslado Adoptivo / Viroterapia Oncolítica Límite: Animals Idioma: En Revista: J Clin Invest Año: 2019 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Melanoma Experimental / Transducción de Señal / Interferón beta / Interferón-alfa / Traslado Adoptivo / Viroterapia Oncolítica Límite: Animals Idioma: En Revista: J Clin Invest Año: 2019 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos