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Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.
Stewart-Jones, Guillaume B E; Chuang, Gwo-Yu; Xu, Kai; Zhou, Tongqing; Acharya, Priyamvada; Tsybovsky, Yaroslav; Ou, Li; Zhang, Baoshan; Fernandez-Rodriguez, Blanca; Gilardi, Valentina; Silacci-Fregni, Chiara; Beltramello, Martina; Baxa, Ulrich; Druz, Aliaksandr; Kong, Wing-Pui; Thomas, Paul V; Yang, Yongping; Foulds, Kathryn E; Todd, John-Paul; Wei, Hui; Salazar, Andres M; Scorpio, Diana G; Carragher, Bridget; Potter, Clinton S; Corti, Davide; Mascola, John R; Lanzavecchia, Antonio; Kwong, Peter D.
Afiliación
  • Stewart-Jones GBE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Chuang GY; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Xu K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Acharya P; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Tsybovsky Y; National Resource for Automated Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY 10027.
  • Ou L; Electron Microscopy Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD 21701.
  • Zhang B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Fernandez-Rodriguez B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Gilardi V; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
  • Silacci-Fregni C; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
  • Beltramello M; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
  • Baxa U; Humabs BioMed SA, a Subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Druz A; Electron Microscopy Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD 21701.
  • Kong WP; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Thomas PV; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Yang Y; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Foulds KE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Todd JP; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Wei H; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Salazar AM; National Resource for Automated Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY 10027.
  • Scorpio DG; Oncovir, Inc., Washington, DC 20008.
  • Carragher B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Potter CS; National Resource for Automated Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY 10027.
  • Corti D; National Resource for Automated Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY 10027.
  • Mascola JR; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
  • Lanzavecchia A; Humabs BioMed SA, a Subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; jmascola@nih.gov lanzavecchia@irb.usi.ch pdkwong@nih.gov.
Proc Natl Acad Sci U S A ; 115(48): 12265-12270, 2018 11 27.
Article en En | MEDLINE | ID: mdl-30420505
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Respirovirus / Vacunas Virales / Proteínas Virales de Fusión / Virus de la Parainfluenza 1 Humana / Virus de la Parainfluenza 2 Humana / Virus de la Parainfluenza 3 Humana / Virus de la Parainfluenza 4 Humana Límite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Respirovirus / Vacunas Virales / Proteínas Virales de Fusión / Virus de la Parainfluenza 1 Humana / Virus de la Parainfluenza 2 Humana / Virus de la Parainfluenza 3 Humana / Virus de la Parainfluenza 4 Humana Límite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos