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The association of 18F-FDG PET/CT and biomarkers in confirming coronary microvascular dysfunction.
Mayala, Henry Anselmo; Bakari, Khamis Hassan; Mkangala, Abdalah; Magesa, Mafuru; Mghanga, Fabian Pius; ZhaoHui, Wang.
Afiliación
  • Mayala HA; Department of Cardiology 10th Floor, Wuhan Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, 501 Building, Hankou, Wuhan, 43000, Hubei Province, China. mayalahenry29@gmail.com.
  • Bakari KH; Department of Radiology and Nuclear Medicine, Wuhan Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Mkangala A; Department of Radiology and Nuclear Medicine, Wuhan Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Magesa M; Department of Clinical Pharmacology, Wuhan Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Mghanga FP; Department of Internal Medicine, Archbishop James University College, Songea, Tanzania.
  • ZhaoHui W; Department of Cardiology 10th Floor, Wuhan Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, 501 Building, Hankou, Wuhan, 43000, Hubei Province, China.
BMC Res Notes ; 11(1): 796, 2018 Nov 06.
Article en En | MEDLINE | ID: mdl-30400961
OBJECTIVE: The purpose of this study is to evaluate the association between PET/CT CFR and biomarkers combined in confirming the diagnosis of coronary microvascular dysfunction. RESULTS: A total of 28 patients (21 males and 7 females) were included in this descriptive observational study (both qualitative and quantitative). The mean patient age was 55.50 ± 10.21 years (range 27-70 years) and the median was 56.5 years (range 49-63 years). All patients underwent Echo, CAG and PET/CT scan. Chest tightness was the most common symptom in our study. Most patients had normal blood pressure (n = 18, 64.3%) while only (n = 10, 37.5%) had hypertension, and (n = 1, 3.6%) had diabetes mellitus. The mean HDL in CMVD (n = 25) and non-CMVD (n = 3) were 1.30 ± 0.39 and 1.08 ± 0.95, respectively, indicating that the difference between the groups was statistically significant (p = 0.04). Similarly, the mean HBA1c- (glycated haemoglobin) in CMVD (n = 25) and non-CMVD (n = 3) were 5.6 ± 0.53 and 5.0 ± 0.26, respectively, with (p = 0.03). Our findings managed to show the association between biomarkers and PET/CT CFR in confirming the diagnosis of coronary microvascular dysfunction.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Biomarcadores / Circulación Coronaria / Diabetes Mellitus / Tomografía Computarizada por Tomografía de Emisión de Positrones / Hipertensión / Microcirculación Tipo de estudio: Observational_studies / Qualitative_research / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Res Notes Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Biomarcadores / Circulación Coronaria / Diabetes Mellitus / Tomografía Computarizada por Tomografía de Emisión de Positrones / Hipertensión / Microcirculación Tipo de estudio: Observational_studies / Qualitative_research / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Res Notes Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido