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Lower Urinary Tract Function in Familial Spastic Paraplegia.
Sakakibara, Ryuji; Shimizu, Ayami; Takahashi, Osamu; Tateno, Fuyuki; Kishi, Masahiko; Aiba, Yosuke; Suzuki, Hiroyoshi; Yamamoto, Tatsuya; Shibata, Chiharu; Yamanishi, Tomonori.
Afiliación
  • Sakakibara R; Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan, sakakibara@sakura.med.toho-u.ac.jp.
  • Shimizu A; Clinical Physiology Unit, Sakura Medical Center, Toho University, Sakura, Japan.
  • Takahashi O; Clinical Physiology Unit, Sakura Medical Center, Toho University, Sakura, Japan.
  • Tateno F; Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan.
  • Kishi M; Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan.
  • Aiba Y; Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan.
  • Suzuki H; Department of Urology, Sakura Medical Center, Toho University, Sakura, Japan.
  • Yamamoto T; Neurology, Chiba University, Chiba, Japan.
  • Shibata C; Continence Center, Dokkyo Medical College, Tochigi, Japan.
  • Yamanishi T; Continence Center, Dokkyo Medical College, Tochigi, Japan.
Eur Neurol ; 80(3-4): 121-125, 2018.
Article en En | MEDLINE | ID: mdl-30391939
In order to investigate lower urinary tract function in hereditary spastic paraplegia (HSP), we recruited 12 HSP patients: 8 men, 4 women; mean age, 64.6 years; mean disease duration, 18.9 years; walk without cane, 2, walk with cane, 6, wheelchair bound, 3. We performed urinary symptom questionnaires and a urodynamic testing in all patients. As a result, urinary symptoms were observed in all but 3, including urinary urgency/frequency (also called overactive bladder) in 9 and hesitancy/poor stream in 6. Urodynamic abnormalities included detrusor overactivity during bladder filling in 10, underactive detrusor on voiding in 8 (detrusor hyperactivity with impaired contraction [DHIC] in 5), detrusor-sphincter dyssynergia (DSD) on voiding in 3, and post-void residual in 5. Sphincter electromyography showed neurogenic motor unit potential in 4. In conclusion, we observed high frequency of urinary symptoms in HSP. Urodynamics indicated that the main mechanism is DHIC with/without DSD for their urinary symptom, and sacral cord involvement in some cases. These findings facilitate patients' care including clean, intermittent catheterization.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos Urinarios / Paraplejía Espástica Hereditaria Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur Neurol Año: 2018 Tipo del documento: Article Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos Urinarios / Paraplejía Espástica Hereditaria Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur Neurol Año: 2018 Tipo del documento: Article Pais de publicación: Suiza