Your browser doesn't support javascript.
loading
'Test n Treat' (TnT): a cluster randomized feasibility trial of on-site rapid Chlamydia trachomatis tests and treatment in ethnically diverse, sexually active teenagers attending technical colleges.
Oakeshott, P; Kerry-Barnard, S; Fleming, C; Phillips, R; Drennan, V M; Adams, E J; Majewska, W; Harding-Esch, E M; Cousins, E C; Planche, T; Green, A; Bartholomew, R I; Sadiq, S T; Reid, F.
Afiliación
  • Oakeshott P; Population Health Research Institute, St George's, University of London, London UK. Electronic address: oakeshot@sgul.ac.uk.
  • Kerry-Barnard S; Population Health Research Institute, St George's, University of London, London UK.
  • Fleming C; Population Health Research Institute, St George's, University of London, London UK.
  • Phillips R; School of Population Health and Environmental Sciences, King's College London, London, UK.
  • Drennan VM; Centre for Health & Social Care Research, Kingston University & St George's, University of London, London, UK.
  • Adams EJ; Aquarius Population Health Limited, London, UK.
  • Majewska W; WEM Consultancy Ltd, London, UK.
  • Harding-Esch EM; Institute for Infection and Immunity, St George's, University of London, London, UK; Public Health England, London, UK.
  • Cousins EC; Institute for Infection and Immunity, St George's, University of London, London, UK.
  • Planche T; Institute for Infection and Immunity, St George's, University of London, London, UK.
  • Green A; Population Health Research Institute, St George's, University of London, London UK.
  • Bartholomew RI; Population Health Research Institute, St George's, University of London, London UK; Institute for Infection and Immunity, St George's, University of London, London, UK.
  • Sadiq ST; Institute for Infection and Immunity, St George's, University of London, London, UK.
  • Reid F; School of Population Health and Environmental Sciences, King's College London, London, UK.
Clin Microbiol Infect ; 25(7): 865-871, 2019 Jul.
Article en En | MEDLINE | ID: mdl-30391581
OBJECTIVES: We conducted a cluster-randomized feasibility trial of 90-minute Chlamydia trachomatis tests and same day on-site treatment ('Test n Treat/TnT') in six technical colleges in London, England, to assess TnT uptake rates; follow-up rates; prevalence of C. trachomatis at baseline and 7 months; time to treatment; acceptability of TnT. METHODS: Participants completed questionnaires and provided genitourinary samples at baseline and 7 months. Participants were informed that baseline samples would not be tested for 7 months and were advised to get screened independently. Colleges were randomly allocated 1:1 to intervention (TnT) or control (no TnT). One month and 4 months post recruitment, participants at intervention colleges were texted invitations for on-site free C. trachomatis tests. A purposive sample of students who did/did not attend for screening were interviewed (n = 26). RESULTS: Five hundred and nine sexually active students were recruited: median age 17.9 years, 47% male, 50% black ethnicity, 55% reporting two or more sexual partners in the previous year. TnT uptake was 13% (33/259; 95% CI 8.9-17.4%) at 1 month and 10% (26/259; 6.7-14.4%) at 4 months with overall C. trachomatis positivity 5.1% (3/59; 1.1-14.2%). Follow-up at 7 months was 62% (317/509) for questionnaires and 52% (264/509) for samples. C. trachomatis prevalence was 6.2% (31/503) at baseline and 6.1% (16/264) at 7 months. Median time from test to treatment was 15 h. Interviews suggested low test uptake was associated with not feeling at risk, perceptions of stigma, and little knowledge of sexually transmitted infections (STIs). CONCLUSIONS: Despite high C. trachomatis rates at baseline and follow-up, uptake of testing was low. Like many countries, England urgently needs better sex education, including making STI testing routine/normal. Trial registration ISRCTN58038795.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Chlamydia / Enfermedades de Transmisión Sexual / Chlamydia trachomatis Tipo de estudio: Clinical_trials / Etiology_studies / Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Clin Microbiol Infect Asunto de la revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Chlamydia / Enfermedades de Transmisión Sexual / Chlamydia trachomatis Tipo de estudio: Clinical_trials / Etiology_studies / Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Clin Microbiol Infect Asunto de la revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido