Your browser doesn't support javascript.
loading
Comparative analysis of blood parameters of the erythrocyte lineage between patients with chronic periodontitis and healthy patients: Results obtained from a meta-analysis.
França, Luiz Felipe de Carvalho; da Silva, Felipe Rodolfo Pereira; di Lenardo, David; Alves, Even Herlany Pereira; Nascimento, Hélio Mateus Silva; da Silva, Isabela Aparecida Tito; Vasconcelos, Any Carolina Cardoso Guimarães; Vasconcelos, Daniel Fernando Pereira.
Afiliación
  • França LFC; Post-Graduate Program in Biomedical Sciences, Federal University of Piaui, Parnaiba, Piaui, Brazil.
  • da Silva FRP; Post-Graduate Program in Biomedical Sciences, Federal University of Piaui, Parnaiba, Piaui, Brazil.
  • di Lenardo D; Post-Graduate Program in Biomedical Sciences, Federal University of Piaui, Parnaiba, Piaui, Brazil.
  • Alves EHP; Post-Graduate Program in Biotechnology, Federal University of Piaui, Parnaiba, Piaui, Brazil.
  • Nascimento HMS; Laboratory of Analysis and Histological Processing (LAPHIS), Federal University of Piaui, Parnaiba, Piaui, Brazil.
  • da Silva IAT; Post-Graduate Program in Biomedical Sciences, Federal University of Piaui, Parnaiba, Piaui, Brazil.
  • Vasconcelos ACCG; Medicine School, Education Institute of Parnaiba Valley (IESVAP), Parnaiba, Piaui, Brazil.
  • Vasconcelos DFP; Post-Graduate Program in Biomedical Sciences, Federal University of Piaui, Parnaiba, Piaui, Brazil. Electronic address: vasconcelos@ufpi.edu.br.
Arch Oral Biol ; 97: 144-149, 2019 Jan.
Article en En | MEDLINE | ID: mdl-30388570
Objective Quantitatively evaluate blood parameters of the erythrocyte lineage in patients with chronic periodontitis and healthy controls by means of a meta-analysis. Material and methods A review of literature was performed in the scientific databases for studies published before September 2016. The abstracts were evaluated and the extraction of data performed by two examiners. The parameters assessed were: hemoglobin levels, number of circulating red blood cells, hematocrit, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration in patients with chronic periodontitis and healthy controls. The calculations were obtained through the statistical software Review Manager version 5.3, with calculation of Mean Difference, heterogeneity (I²) and funnel plot with P < 0.05. Results Nine case/control studies composed the results with 342 patients with chronic periodontitis and 359 healthy controls. There was a significant decrease in hemoglobin levels (MD = -1.60, 95% CI: -2.72, -0.48, P = 0.005) and number of circulating red blood cells (MD = -0.51, 95% CI: -0.78, -0.24, P = 0.0002), hematocrit (MD = -4.41, IC 95%: -7.13, -1.68, P = 0.002), mean corpuscular hemoglobin (MD = -0.80; IC 95%: -1.38, -0,22, P = 0.007) and mean corpuscular hemoglobin concentration (MD = -0.93, IC 95%: -1.63, -0.23, P = 0.009) in patients with chronic periodontitis when compared to healthy controls. No publication bias was found through the funnel plot asymmetry. Conclusion There is an associated of the reduction of hematological parameters (such as levels of hemoglobin and circulating red blood cells, hematocrit, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration) to patients with chronic periodontitis.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índices de Eritrocitos / Periodontitis Crónica Tipo de estudio: Observational_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Arch Oral Biol Año: 2019 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índices de Eritrocitos / Periodontitis Crónica Tipo de estudio: Observational_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Arch Oral Biol Año: 2019 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido