Myostatin induces tumor necrosis factor-&#945; expression in rheumatoid arthritis synovial fibroblasts through the PI3K-Akt signaling pathway.

Su, Chen-Ming; Hu, Sung-Lin; Sun, Yi; Zhao, Jin; Dai, Chengqian; Wang, Lihong; Xu, Guohong; Tang, Chih-Hsin

Myostatin induces tumor necrosis factor-α expression in rheumatoid arthritis synovial fibroblasts through the PI3K-Akt signaling pathway.

Su, Chen-Ming; Hu, Sung-Lin; Sun, Yi; Zhao, Jin; Dai, Chengqian; Wang, Lihong; Xu, Guohong; Tang, Chih-Hsin.

Afiliación

Su CM; Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, China.
Hu SL; Program for Aging, China Medical University, Taichung, Taiwan.
Sun Y; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.
Zhao J; Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, China.
Dai C; Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, China.
Wang L; Department of Orthopedics, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, China.
Xu G; Department of Orthopedics, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, China.
Tang CH; Department of Orthopedics, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, China.

J Cell Physiol ; 234(6): 9793-9801, 2019 06.

Article en En | MEDLINE | ID: mdl-30378113

Asunto(s)

Artritis Reumatoide/metabolismo; Fibroblastos/metabolismo; Miostatina/farmacología; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo; Línea Celular; Regulación de la Expresión Génica/efectos de los fármacos; Humanos; Fosfatidilinositol 3-Quinasas/genética; Proteínas Proto-Oncogénicas c-akt/genética; Transducción de Señal; Membrana Sinovial/efectos de los fármacos; Membrana Sinovial/metabolismo; Factor de Transcripción AP-1/genética; Factor de Transcripción AP-1/metabolismo; Factor de Necrosis Tumoral alfa/genética

Palabras clave

c-Jun; myostatin; rheumatoid arthritis; tumor necrosis factor-α

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Factor de Necrosis Tumoral alfa / Fosfatidilinositol 3-Quinasas / Proteínas Proto-Oncogénicas c-akt / Miostatina / Fibroblastos Límite: Humans Idioma: En Revista: J Cell Physiol Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google