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Synapse Type-Dependent Expression of Calcium-Permeable AMPA Receptors.
Lalanne, Txomin; Oyrer, Julia; Farrant, Mark; Sjöström, P Jesper.
Afiliación
  • Lalanne T; Department of Biomedicine, Institute of Physiology, University of Basel, Basel, Switzerland.
  • Oyrer J; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia.
  • Farrant M; Department of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
  • Sjöström PJ; Centre for Research in Neuroscience, Department of Neurology and Neurosurgery, Brain Repair and Integrative Neuroscience Program, Montreal General Hospital, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
Front Synaptic Neurosci ; 10: 34, 2018.
Article en En | MEDLINE | ID: mdl-30369875
Calcium-permeable (CP) AMPA-type glutamate receptors (AMPARs) are known to mediate synaptic plasticity in several different interneuron (IN) types. Recent evidence suggests that CP-AMPARs are synapse-specifically expressed at excitatory connections onto a subset of IN types in hippocampus and neocortex. For example, CP-AMPARs are found at connections from pyramidal cells (PCs) to basket cells (BCs), but not to Martinotti cells (MCs). This synapse type-specific expression of CP-AMPARs suggests that synaptic dynamics as well as learning rules are differentially implemented in local circuits and has important implications not just in health but also in disease states such as epilepsy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Synaptic Neurosci Año: 2018 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Synaptic Neurosci Año: 2018 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Suiza