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Long-Term in Situ Reduction in Soil Lead Bioavailability Measured in a Mouse Model.
Bradham, Karen D; Diamond, Gary L; Nelson, Clay M; Noerpel, Matt; Scheckel, Kirk G; Elek, Brittany; Chaney, Rufus L; Ma, Qing; Thomas, David J.
Afiliación
  • Bradham KD; Office of Research and Development , United States Environmental Protection Agency (U.S. EPA) , Research Triangle Park , North Carolina 27711 , United States.
  • Diamond GL; SRC, Inc. , North Syracuse , New York 13212 , United States.
  • Nelson CM; Office of Research and Development , United States Environmental Protection Agency (U.S. EPA) , Research Triangle Park , North Carolina 27711 , United States.
  • Noerpel M; Office of Research and Development , United States Environmental Protection Agency (U.S. EPA) , Cincinnati , Ohio 45224 , United States.
  • Scheckel KG; Office of Research and Development , United States Environmental Protection Agency (U.S. EPA) , Cincinnati , Ohio 45224 , United States.
  • Elek B; Pharmacokinetics Branch, Integrated Systems Toxicology Division, National Health and Environmental Effects Laboratory, ORD , US EPA , Research Triangle Park , North Carolina 27709 , United States.
  • Chaney RL; USDA-ARS-Adaptive Cropping Systems Lab , Beltsville , Maryland 20705 , United States.
  • Ma Q; DND-CAT , Synchrotron Research Center-Northwestern University at the Advanced Photon Source , Argonne , Illinois 60439 , United States.
  • Thomas DJ; Pharmacokinetics Branch, Integrated Systems Toxicology Division, National Health and Environmental Effects Laboratory, ORD , US EPA , Research Triangle Park , North Carolina 27709 , United States.
Environ Sci Technol ; 52(23): 13908-13913, 2018 12 04.
Article en En | MEDLINE | ID: mdl-30358995
Effects of different treatments on the bioavailability of lead (Pb) in soil from a smelter emission contaminated site in Joplin, Missouri, were evaluated in a mouse model. Similar estimates of relative bioavailability for Pb in untreated or treated soil were obtained in mice and in the well-established juvenile swine model. In the mouse model, treatments that used phosphate (phosphoric acid or triple superphosphate) combined with iron oxide or biosolids compost significantly reduced soil Pb bioavailability. Notably, effects of these remediation procedures were persistent, given that up to 16 years had elapsed between soil treatment and sample collection. Remediation of soils was associated with changes in Pb species present in soil. Differences in Pb species in ingested soil and in feces from treated mice indicated that changes in Pb speciation occurred during transit through the gastrointestinal tract. Use of the mouse model facilitates evaluation of remediation procedures and allows monitoring of the performance of procedures under laboratory and field conditions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Suelo / Contaminantes del Suelo Límite: Animals País/Región como asunto: America do norte Idioma: En Revista: Environ Sci Technol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Suelo / Contaminantes del Suelo Límite: Animals País/Región como asunto: America do norte Idioma: En Revista: Environ Sci Technol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos