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Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis.
Scott, Nicholas A; Andrusaite, Anna; Andersen, Peter; Lawson, Melissa; Alcon-Giner, Cristina; Leclaire, Charlotte; Caim, Shabhonam; Le Gall, Gwenaelle; Shaw, Tovah; Connolly, James P R; Roe, Andrew J; Wessel, Hannah; Bravo-Blas, Alberto; Thomson, Carolyn A; Kästele, Verena; Wang, Ping; Peterson, Daniel A; Bancroft, Allison; Li, Xuhang; Grencis, Richard; Mowat, Allan McI; Hall, Lindsay J; Travis, Mark A; Milling, Simon W F; Mann, Elizabeth R.
Afiliación
  • Scott NA; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, UK.
  • Andrusaite A; Manchester Collaborative Centre for Inflammation Research, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, UK.
  • Andersen P; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
  • Lawson M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Alcon-Giner C; Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UA, UK.
  • Leclaire C; Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UA, UK.
  • Caim S; Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UA, UK.
  • Le Gall G; Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UA, UK.
  • Shaw T; Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UA, UK.
  • Connolly JPR; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, UK.
  • Roe AJ; Manchester Collaborative Centre for Inflammation Research, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, UK.
  • Wessel H; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
  • Bravo-Blas A; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
  • Thomson CA; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
  • Kästele V; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
  • Wang P; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
  • Peterson DA; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
  • Bancroft A; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, UK.
  • Li X; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Grencis R; Eli Lilly and Company, Indianapolis, 46285 IN, USA.
  • Mowat AM; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, UK.
  • Hall LJ; Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester M13 9PT, UK.
  • Travis MA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Milling SWF; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, UK.
  • Mann ER; Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester M13 9PT, UK.
Sci Transl Med ; 10(464)2018 10 24.
Article en En | MEDLINE | ID: mdl-30355800
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T / Homeostasis / Inmunidad Innata / Intestinos / Macrófagos / Antibacterianos Límite: Animals Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T / Homeostasis / Inmunidad Innata / Intestinos / Macrófagos / Antibacterianos Límite: Animals Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos