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Molecular epidemiology of human papillomavirus genotypes in oral rinses from HIV-positive and HIV-negative Jamaican patients.
Rajendra Santosh, Arvind B; Christian, Nicole A; Jones, Thaon; Thoms-Rodriguez, Camille-Ann A; Condappa, Andrew; Thompson, Tamara; Pinkney, Jodian; Barton, Everard N; Lindo, John.
Afiliación
  • Rajendra Santosh AB; School of Dentistry, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
  • Christian NA; Department of Microbiology, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
  • Jones T; School of Dentistry, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
  • Thoms-Rodriguez CA; Department of Microbiology, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
  • Condappa A; Department of Basic Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
  • Thompson T; Department of Medicine, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
  • Pinkney J; Department of Medicine, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
  • Barton EN; Department of Medicine, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
  • Lindo J; Department of Microbiology, Faculty of Medical Sciences, The University of the West Indies, Kingston, Jamaica.
J Investig Clin Dent ; 10(1): e12365, 2019 Feb.
Article en En | MEDLINE | ID: mdl-30338674
AIM: Human papillomavirus (HPV) has been reported to be associated with oral and oropharyngeal cancer. However, little information is available about the epidemiology of oral HPV infection in Jamaica. The purpose of the present study was to assess the prevalence of oral HPV strains using the oral rinse method in HIV and non-HIV Jamaican patients, as well as to determine the association of HPV with sexual practices, smoking, and alcohol use. METHODS: A cross-sectional study was conducted on patients attending The University of the West Indies Mona Dental Polyclinic and the Centre for HIV/AIDS Research and Education Services. Salivary samples were tested through molecular analysis for 37 HPV genotypes using the linear array HPV genotyping test. A survey questionnaire was used to obtain demographic details, smoking history, alcohol practice, sexual practice, and history of HPV testing. RESULTS: The HPV prevalence was 8.65% in 18-64 y olds (N = 104), with a slight female predilection (55%). No high-risk HPV types were found. HPV-84 was the most common type in both HIV and non-HIV patients; 66.7% of HPV-positive participants reported that they had six or more lifetime sexual partners. CONCLUSION: The prevalence of oral HPV was similar to that in other countries. No statistically-significant relationship was observed between the prevalence of HPV and either the number of sexual partners, smoking, or alcohol history. A nationwide study on oral HPV detection might be helpful in developing a HPV vaccination policy in Jamaica.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Papillomaviridae / Infecciones por VIH / Epidemiología Molecular / Infecciones por Papillomavirus / Genotipo / Antisépticos Bucales Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Caribe ingles / Jamaica Idioma: En Revista: J Investig Clin Dent Año: 2019 Tipo del documento: Article País de afiliación: Jamaica Pais de publicación: Australia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Papillomaviridae / Infecciones por VIH / Epidemiología Molecular / Infecciones por Papillomavirus / Genotipo / Antisépticos Bucales Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Caribe ingles / Jamaica Idioma: En Revista: J Investig Clin Dent Año: 2019 Tipo del documento: Article País de afiliación: Jamaica Pais de publicación: Australia