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Combinations of BRAF inhibitor and anti-PD-1/PD-L1 antibody improve survival and tumour immunity in an immunocompetent model of orthotopic murine anaplastic thyroid cancer.
Gunda, Viswanath; Gigliotti, Benjamin; Ndishabandi, Dorothy; Ashry, Tameem; McCarthy, Michael; Zhou, Zhiheng; Amin, Salma; Freeman, Gordon J; Alessandrini, Alessandro; Parangi, Sareh.
Afiliación
  • Gunda V; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Gigliotti B; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Ndishabandi D; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Ashry T; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • McCarthy M; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Zhou Z; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Amin S; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Alessandrini A; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Parangi S; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. sparangi@mgh.harvard.edu.
Br J Cancer ; 119(10): 1223-1232, 2018 11.
Article en En | MEDLINE | ID: mdl-30327563
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sulfonamidas / Neoplasias de la Tiroides / Proteínas Proto-Oncogénicas B-raf / Antígeno B7-H1 / Receptor de Muerte Celular Programada 1 / Carcinoma Anaplásico de Tiroides / Indoles / Anticuerpos Monoclonales Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Br J Cancer Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sulfonamidas / Neoplasias de la Tiroides / Proteínas Proto-Oncogénicas B-raf / Antígeno B7-H1 / Receptor de Muerte Celular Programada 1 / Carcinoma Anaplásico de Tiroides / Indoles / Anticuerpos Monoclonales Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Br J Cancer Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido