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Design, synthesis and biological evaluation of 1,4-Diazobicylco[3.2.2]nonane derivatives as α7-Nicotinic acetylcholine receptor PET/CT imaging agents and agonists for Alzheimer's disease.
Wang, Shuxia; Fang, Yu; Wang, Huan; Gao, Hang; Jiang, Guohua; Liu, Jianping; Xue, Qianqian; Qi, Yueheng; Cao, Mengying; Qiang, Bingchao; Zhang, Huabei.
Afiliación
  • Wang S; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Fang Y; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Wang H; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Gao H; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Jiang G; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Liu J; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Xue Q; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Qi Y; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Cao M; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Qiang B; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Zhang H; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China. Electronic address: hbzhang@bnu.edu.cn.
Eur J Med Chem ; 159: 255-266, 2018 Nov 05.
Article en En | MEDLINE | ID: mdl-30296684
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Compuestos Bicíclicos Heterocíclicos con Puentes / Enfermedad de Alzheimer / Receptor Nicotínico de Acetilcolina alfa 7 / Tomografía Computarizada por Tomografía de Emisión de Positrones Límite: Animals / Female / Humans / Male Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Compuestos Bicíclicos Heterocíclicos con Puentes / Enfermedad de Alzheimer / Receptor Nicotínico de Acetilcolina alfa 7 / Tomografía Computarizada por Tomografía de Emisión de Positrones Límite: Animals / Female / Humans / Male Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia