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Sellar Region Atypical Teratoid/Rhabdoid Tumors in Adults: Clinicopathological Characterization of Five Cases and Review of the Literature.
Paolini, Michael A; Kipp, Benjamin R; Sukov, William R; Jenkins, Sarah M; Barr Fritcher, Emily G; Aranda, Derick; SantaCruz, Karen S; Al-Dandan, Sadeq; Fisher, Pete; McDonald, William C; Bondurant, Charles P; Van Dyke Darkow, Grant; Giannini, Caterina; Parisi, Joseph E; Jentoft, Mark E; Raghunathan, Aditya.
Afiliación
  • Paolini MA; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
  • Kipp BR; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
  • Sukov WR; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
  • Jenkins SM; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota.
  • Barr Fritcher EG; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
  • Aranda D; Patient Recruitment Department, Altea Research Institute, Las Vegas, Nevada.
  • SantaCruz KS; Department of Pathology, University of New Mexico, Albuquerque, New Mexico.
  • Al-Dandan S; Department of Anatomical Pathology, King Fahad Medical City, King Saud bin Abdulaziz University, Riyadh, Saudi Arabia.
  • Fisher P; Department of Pathology, North Valley Hospital, Kalispell, Montana.
  • McDonald WC; Department of Pathology and Laboratory Medicine, Allina Health Laboratories, Minneapolis, Minnesota.
  • Bondurant CP; Department of Neurosurgery, Boone Hospital Center, Columbia, Missouri.
  • Van Dyke Darkow G; Boyce and Bynum Pathology Laboratories, Columbia, Missouri.
  • Giannini C; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
  • Parisi JE; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
  • Jentoft ME; Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, Florida.
  • Raghunathan A; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
J Neuropathol Exp Neurol ; 77(12): 1115-1121, 2018 12 01.
Article en En | MEDLINE | ID: mdl-30295777
Atypical teratoid/rhabdoid tumors (AT/RTs) are highly malignant CNS neoplasms that typically occur in children <2 years of age. These are characterized by high-grade histologic features and mutations of the INI1/SMARCB1 gene readily detected by loss of expression by immunohistochemistry. Among adults, the majority of AT/RTs occurs in the cerebral hemispheres. A small number of adult AT/RTs involving the sellar and suprasellar region reported in the literature suggest a distinct clinical course for this group. Here, we describe detailed clinical and genetic characterization of 5 adult patients with AT/RTs involving the sellar and suprasellar region, and provide a review of the available clinical and genetic features of 22 previously reported cases in order to help increase our understanding of this unusual entity.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Silla Turca / Teratoma / Tumor Rabdoide Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neuropathol Exp Neurol Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Silla Turca / Teratoma / Tumor Rabdoide Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neuropathol Exp Neurol Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido