Your browser doesn't support javascript.
loading
Phytochemical screening and antityrosinase activity of carvacrol, thymoquinone, and four essential oils of Lebanese plants.
El Khoury, Rindala; Michael Jubeli, Rime; El Beyrouthy, Marc; Baillet Guffroy, Arlette; Rizk, Toufic; Tfayli, Ali; Lteif, Roger.
Afiliación
  • El Khoury R; Unité de Technologie et Valorisation Alimentaire, Centre d'Analyses et de Recherche, Université Saint-Joseph, Beirut, Lebanon.
  • Michael Jubeli R; Interdisciplinary Unit: Lipids, Analytical and Biological Systems Lip(Sys), Faculty of Pharmacy, Univ Paris-Sud, Univ Paris-Saclay, Châtenay-Malabry, France.
  • El Beyrouthy M; Obegi Chemicals, Beirut, Lebanon.
  • Baillet Guffroy A; Interdisciplinary Unit: Lipids, Analytical and Biological Systems Lip(Sys), Faculty of Pharmacy, Univ Paris-Sud, Univ Paris-Saclay, Châtenay-Malabry, France.
  • Rizk T; Faculty of Agriculture and Food Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon.
  • Tfayli A; Interdisciplinary Unit: Lipids, Analytical and Biological Systems Lip(Sys), Faculty of Pharmacy, Univ Paris-Sud, Univ Paris-Saclay, Châtenay-Malabry, France.
  • Lteif R; Unité de Technologie et Valorisation Alimentaire, Centre d'Analyses et de Recherche, Université Saint-Joseph, Beirut, Lebanon.
J Cosmet Dermatol ; 18(3): 944-952, 2019 Jun.
Article en En | MEDLINE | ID: mdl-30291663
OBJECTIVE: In our study, we aim to explore the ability of four essential oils (EO) of Lebanese plants to inhibit the tyrosinase activity and to correlate their efficiency level to their phytochemical compositions. METHODS: The EO have been extracted by hydrodistillation using a Clevenger apparatus and have been studied by GC-MS analysis. Active compounds of Origanum species were identified and antityrosinase activities of EO and active molecules (carvacrol and thymoquinone) have been tested in tubo. RESULTS: Antityrosinase activities were obtained as follows: EO of Origanum syriacum (80.41% ± 2.00%), EO of Origanum ehrenbergii (45.33% ± 2.20%), EO of Salvia fruticosa (14.62% ± 2.30%), EO of Calamintha origanifolia (16.51% ± 5.80%), Carvacrol (56.55% ± 3.10%), and Thymoquinone (19.49% ± 1.50%). CONCLUSION: Origanum essential oils resulted in the highest antityrosinase activity due to their high content in carvacrol. However, when present together with carvacrol, thymoquinone decreases the efficiency of carvacrol, which is the case of O. ehrenbergii essential oil. Thus, for improved antityrosinase activity, O. syriacum and O. ehrenbergii should be harvested during flowering stage where carvacrol is present at its highest dosage and thymoquinone at its lowest.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceites de Plantas / Aceites Volátiles / Monofenol Monooxigenasa / Preparaciones para Aclaramiento de la Piel Tipo de estudio: Diagnostic_studies / Screening_studies País/Región como asunto: Asia Idioma: En Revista: J Cosmet Dermatol Asunto de la revista: DERMATOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Líbano Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceites de Plantas / Aceites Volátiles / Monofenol Monooxigenasa / Preparaciones para Aclaramiento de la Piel Tipo de estudio: Diagnostic_studies / Screening_studies País/Región como asunto: Asia Idioma: En Revista: J Cosmet Dermatol Asunto de la revista: DERMATOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Líbano Pais de publicación: Reino Unido