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Genetics and pharmacogenetics of estrogen response.
Carbonell Sala, Silvia; Martineti, Valentina; Carossino, Anna Maria; Brandi, Maria Luisa.
Afiliación
  • Carbonell Sala S; a University of Florence, Department of Internal Medicine, Florence, Italy; DeGene Spin-Off, Viale Pieraccini, 6-50139, Florence, Italy. s.carbonell@dmi.unifi.it.
  • Martineti V; b University of Florence, Department of Internal Medicine, Florence, Italy. v.martineti@dmi.unifi.it.
  • Carossino AM; c University of Florence, Department of Internal Medicine, Florence, Italy. a.carossino@dmi.unifi.it.
  • Brandi ML; d University of Florence, Department of Internal Medicine, Florence, Italy; De Gene Spin-Off, Viale Pieraccini, 6-50139, Florence, Italy. m.brandi@dmi.unifi.it.
Expert Rev Endocrinol Metab ; 2(4): 503-516, 2007 Jul.
Article en En | MEDLINE | ID: mdl-30290424
Estrogens are a steroid hormone group distributed widely in animals and human beings. Estrogens diffuse across cell phospholipidic membranes and interact with estrogen receptors. Their highest concentration is found in target tissues with reproductive function (breast, ovary, vagina and uterus). High estrogen levels are usually associated with tumor onset and progression, while loss of estrogen or its receptor(s) contributes to development and/or progression of various diseases (osteoporosis, neurodegenerative disease and cardiovascular disease). Despite the numerous efforts to highlight estrogen's mechanism of action, recent discoveries showed an unexpected degree of complexity of estrogenic response.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Expert Rev Endocrinol Metab Año: 2007 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Expert Rev Endocrinol Metab Año: 2007 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido