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Spinal Coccidioidomycosis: MR Imaging Findings in 41 Patients.
Crete, R N; Gallmann, W; Karis, J P; Ross, J.
Afiliación
  • Crete RN; From the Department of Neuroradiology (R.N.C., W.G., J.P.K.), Barrow Neurological Institute, Phoenix, Arizona Danielle.Andazola@dignityhealth.org.
  • Gallmann W; From the Department of Neuroradiology (R.N.C., W.G., J.P.K.), Barrow Neurological Institute, Phoenix, Arizona.
  • Karis JP; From the Department of Neuroradiology (R.N.C., W.G., J.P.K.), Barrow Neurological Institute, Phoenix, Arizona.
  • Ross J; Department of Radiology (J.R.), Mayo Clinic College of Medicine, Phoenix, Arizona.
AJNR Am J Neuroradiol ; 39(11): 2148-2153, 2018 11.
Article en En | MEDLINE | ID: mdl-30287458
BACKGROUND AND PURPOSE: Coccidioides immitis is a dimorphic fungus endemic to the Southwest United States and Mexico, and at our institution, it is a relatively common pathogen presenting with a broad spectrum of associated spine diseases. We describe the various spinal manifestations resulting from coccidioidal infection and provide MR imaging examples from 41 pathologically proved cases. MATERIALS AND METHODS: Retrospective electronic medical record and PACS searches were performed. Patients found to have both MR imaging findings positive for infection and confirmative biopsy and/or CSF studies were included. Abnormal MR imaging findings were identified, categorized, and quantified. Patient demographics and associated intracranial involvement if present were also recorded. RESULTS: Forty-one patients were included. Positive findings were categorized as leptomeningeal enhancement (26 patients, 63%), arachnoiditis (22 patients, 54%), osteomyelitis-discitis (14 patients, 34%), cord edema (11 patients, 27%), and true syrinx (3 patients, 7%). Thirty patients had documented brain involvement (73%), most commonly in the form of basilar meningitis. Four patients were positive for HIV (10%). Fifteen patients had pulmonary manifestations at presentation (37%). CONCLUSIONS: C immitis results in various spinal manifestations, most commonly leptomeningeal enhancement and arachnoiditis/adhesive disease followed by osteomyelitis, which may resemble tuberculous or pyogenic infection on MR imaging.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Médula Espinal / Enfermedades de la Columna Vertebral / Coccidioidomicosis Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: AJNR Am J Neuroradiol Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Médula Espinal / Enfermedades de la Columna Vertebral / Coccidioidomicosis Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: AJNR Am J Neuroradiol Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos