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The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum.
Soma-Pillay, P; Pillay, R; Wong, T Y; Makin, J D; Pattinson, R C.
Afiliación
  • Soma-Pillay P; Department of Obstetrics and Gynaecology, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa.
  • Pillay R; South African Medical Research Council Maternal and Infant Health Care Strategies Unit, Department of Obstetrics and Gynaecology, University of Pretoria, Pretoria, South Africa.
  • Wong TY; Netcare Waterfall Hospital, Midrand, South Africa.
  • Makin JD; Sunninghill Hospital, Sandton, South Africa.
  • Pattinson RC; Singapore Eye Research Institute, Singapore, Singapore.
Obstet Med ; 11(3): 116-120, 2018 Sep.
Article en En | MEDLINE | ID: mdl-30214476
BACKGROUND: The retinal microcirculation provides a unique view of microvessel structure by means of non-invasive, retinal image analysis. The aim of the study was to compare the retinal vessel caliber at delivery and one-year post-partum between women who have had pre-eclampsia during pregnancy to a normotensive control group. METHODS: Digital photos of the eye were taken at delivery and one-year post-partum. Retinal vessels were analysed and summarised as the corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent. RESULTS: The corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent were significantly lower in the pre-eclamptic group compared to the control group both at delivery and one-year post-partum (p < 0.001). CONCLUSION: Retinal artery and venular caliber changes that occur during pregnancies affected by pre-eclampsia persist for up to one-year post-partum. These changes may reflect a permanent, long-term microvascular dysfunction and may be useful as a biomarker of future vascular risk.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Obstet Med Año: 2018 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Obstet Med Año: 2018 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Reino Unido