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Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death.
Garcia-Carbonell, Ricard; Wong, Jerry; Kim, Ju Youn; Close, Lisa Abernathy; Boland, Brigid S; Wong, Thomas L; Harris, Philip A; Ho, Samuel B; Das, Soumita; Ernst, Peter B; Sasik, Roman; Sandborn, William J; Bertin, John; Gough, Pete J; Chang, John T; Kelliher, Michelle; Boone, David; Guma, Monica; Karin, Michael.
Afiliación
  • Garcia-Carbonell R; Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego, CA 92093.
  • Wong J; Department of Pharmacology, University of California, San Diego, CA 92093.
  • Kim JY; Department of Pathology, University of California, San Diego, CA 92093.
  • Close LA; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.
  • Boland BS; Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego, CA 92093.
  • Wong TL; Department of Pharmacology, University of California, San Diego, CA 92093.
  • Harris PA; Department of Pathology, University of California, San Diego, CA 92093.
  • Ho SB; Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego, CA 92093.
  • Das S; Department of Pharmacology, University of California, San Diego, CA 92093.
  • Ernst PB; Department of Pathology, University of California, San Diego, CA 92093.
  • Sasik R; Department of Microbiology and Immunology, Indiana University School of Medicine, South Bend, IN 46617.
  • Sandborn WJ; Department of Medicine, Division of Gastroenterology, University of California, San Diego, CA 92093.
  • Bertin J; Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego, CA 92093.
  • Gough PJ; Department of Pharmacology, University of California, San Diego, CA 92093.
  • Chang JT; Department of Pathology, University of California, San Diego, CA 92093.
  • Kelliher M; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426.
  • Boone D; Department of Medicine, VA San Diego Healthcare System, San Diego, CA 92161.
  • Guma M; Department of Pathology, University of California, San Diego, CA 92093.
  • Karin M; Department of Pathology, University of California, San Diego, CA 92093.
Proc Natl Acad Sci U S A ; 115(39): E9192-E9200, 2018 09 25.
Article en En | MEDLINE | ID: mdl-30209212
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Factor de Necrosis Tumoral alfa / Apoptosis / Proteína Serina-Treonina Quinasas de Interacción con Receptores / Proteína 3 Inducida por el Factor de Necrosis Tumoral alfa / Mucosa Intestinal Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Factor de Necrosis Tumoral alfa / Apoptosis / Proteína Serina-Treonina Quinasas de Interacción con Receptores / Proteína 3 Inducida por el Factor de Necrosis Tumoral alfa / Mucosa Intestinal Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos