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Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel.
Li, Binsen; Ge, Peng; Murray, Kevin A; Sheth, Phorum; Zhang, Meng; Nair, Gayatri; Sawaya, Michael R; Shin, Woo Shik; Boyer, David R; Ye, Shulin; Eisenberg, David S; Zhou, Z Hong; Jiang, Lin.
Afiliación
  • Li B; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA.
  • Ge P; California Nano Systems Institute, UCLA, Los Angeles, CA, 90095, USA.
  • Murray KA; Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, UCLA, Los Angeles, CA, 90095, USA.
  • Sheth P; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA.
  • Zhang M; Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, UCLA, Los Angeles, CA, 90095, USA.
  • Nair G; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA.
  • Sawaya MR; Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, UCLA, Los Angeles, CA, 90095, USA.
  • Shin WS; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA.
  • Boyer DR; Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, UCLA, Los Angeles, CA, 90095, USA.
  • Ye S; California Nano Systems Institute, UCLA, Los Angeles, CA, 90095, USA.
  • Eisenberg DS; Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, UCLA, Los Angeles, CA, 90095, USA. david@mbi.ucla.edu.
  • Zhou ZH; California Nano Systems Institute, UCLA, Los Angeles, CA, 90095, USA. hong.zhou@ucla.edu.
  • Jiang L; Department of Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, CA, 90095, USA. hong.zhou@ucla.edu.
Nat Commun ; 9(1): 3609, 2018 09 06.
Article en En | MEDLINE | ID: mdl-30190461
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alfa-Sinucleína Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alfa-Sinucleína Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido