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Vital Bone Formation After Grafting of Autogenous Bone and Biphasic Calcium Phosphate Bioceramic in Extraction Sockets of Rats: Histological, Histometric, and Immunohistochemical Evaluation.
Macedo, Rander Moreira; Lacerda, Suzie Aparecida; Okamoto, Roberta; Shahdad, Shakeel; Brentegani, Luiz Guilherme.
Afiliación
  • Macedo RM; Associate Professor, Department of Dentistry, Positivo University, Curitiba, PR, Brazil.
  • Lacerda SA; Associate Professor, Department of Stomatology, Public Health and Forensic Dentistry, School of Dentistry of Ribeirão Preto, USP-University of São Paulo, Ribeirão Preto, SP, Brazil.
  • Okamoto R; Associate Professor, Department of Basic Sciences, School of Dentistry of Aracatuba, UNESP, Universidade Estadual Paulista, Araçatuba, SP, Brazil.
  • Shahdad S; Consultant at The Royal London Dental Hospital, Department of Restorative Dentistry, Barts and The London NHS Trust Honorary Senior Clinical Lecturer at Queen Mary University of London, Barts and The London School of Medicine and Dentistry.
  • Brentegani LG; Professor, Department of Stomatology, Public Health and Forensic Dentistry, School of Dentistry of Ribeirão Preto, USP-University of São Paulo, Ribeirão Preto, SP, Brazil.
Implant Dent ; 27(6): 615-622, 2018 Dec.
Article en En | MEDLINE | ID: mdl-30188365
PURPOSE: The study aimed to investigate through histology, histometry, and immunohistochemistry the vital bone formation after grafting of biphasic calcium phosphate bioceramic (BC) in combination with calvarial autogenous bone into the dental sockets of rats. MATERIALS AND METHODS: Forty-five male rats were submitted to upper right incisor extraction and divided according to the grafted material in: control, bioceramic (BC), and bioceramic + autogenous bone (BC + AB). The animals were killed 7, 21, and 42 days after surgery for histological, histometric, and immunohistochemistry analysis. RESULTS: Histomorphometric results demonstrated, for BC + AB group, formation of trabecular bone between the particles of BCs and autogenous bone, connecting them, as well as higher percentage of vital bone in comparison with BC. Immunohistochemical reactions showed intense labeling for Runx2-positive cells in the group BC + AB. CONCLUSIONS: Autogenous bone was able to stimulate bone turnover enabling a larger amount of vital bone synthesis and can be recommended as a viable grafting material in combination with synthetic biphasic BC.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteogénesis / Materiales Biocompatibles / Cerámica / Trasplante Óseo / Alveolo Dental / Hidroxiapatitas Límite: Animals Idioma: En Revista: Implant Dent Asunto de la revista: ODONTOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteogénesis / Materiales Biocompatibles / Cerámica / Trasplante Óseo / Alveolo Dental / Hidroxiapatitas Límite: Animals Idioma: En Revista: Implant Dent Asunto de la revista: ODONTOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos