Spheroid Size Does not Impact Metabolism of the ß-blocker Propranolol in 3D Intestinal Fish Model.

Langan, Laura M; Owen, Stewart F; Trznadel, Maciej; Dodd, Nicholas J F; Jackson, Simon K; Purcell, Wendy M; Jha, Awadhesh N

Langan, Laura M; Owen, Stewart F; Trznadel, Maciej; Dodd, Nicholas J F; Jackson, Simon K; Purcell, Wendy M; Jha, Awadhesh N.

Afiliación

Langan LM; School of Biological and Marine Sciences, University of Plymouth, Plymouth, United Kingdom.
Owen SF; Global Sustainability, AstraZeneca, Macclesfield, United Kingdom.
Trznadel M; College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Dodd NJF; School of Biomedical and Healthcare Sciences, University of Plymouth, Plymouth, United Kingdom.
Jackson SK; School of Biomedical and Healthcare Sciences, University of Plymouth, Plymouth, United Kingdom.
Purcell WM; Harvard T.H. Chan School of Public Health, Harvard University, Cambridge, MA, United States.
Jha AN; School of Biological and Marine Sciences, University of Plymouth, Plymouth, United Kingdom.

Front Pharmacol ; 9: 947, 2018.

Article en En | MEDLINE | ID: mdl-30186177

Palabras clave

EPR-oximetry; intestine; metabolism; micro-environment; propranolol; spheroids; ß-blocker

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Suiza

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