Targeting Calpain for Heart Failure Therapy: Implications From Multiple Murine Models.

Wang, Yihui; Chen, Biyi; Huang, Chun-Kai; Guo, Ang; Wu, Jennifer; Zhang, Xiaoming; Chen, Rong; Chen, Cheng; Kutschke, William; Weiss, Robert M; Boudreau, Ryan L; Margulies, Kenneth B; Hong, Jiang; Song, Long-Sheng

Targeting Calpain for Heart Failure Therapy: Implications From Multiple Murine Models.

Wang, Yihui; Chen, Biyi; Huang, Chun-Kai; Guo, Ang; Wu, Jennifer; Zhang, Xiaoming; Chen, Rong; Chen, Cheng; Kutschke, William; Weiss, Robert M; Boudreau, Ryan L; Margulies, Kenneth B; Hong, Jiang; Song, Long-Sheng.

Afiliación

Wang Y; Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.
Chen B; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.
Huang CK; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.
Guo A; Department of Veterans Affairs Medical Center, Iowa City, Iowa.
Wu J; Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.
Zhang X; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.
Chen R; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.
Chen C; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.
Kutschke W; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.
Weiss RM; Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.
Boudreau RL; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.
Margulies KB; Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.
Hong J; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.
Song LS; Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa.

JACC Basic Transl Sci ; 3(4): 503-517, 2018 Aug.

Article en En | MEDLINE | ID: mdl-30175274

Palabras clave

CAPN1-OE, calpain-1 overexpressing; E-C coupling, excitation-contraction coupling; EF, ejection fraction; IP, intraperitoneally; ISO, isoproterenol; JP2, junctophilin-2; JP2-OE, junctophilin-2 overexpressing; LV, left ventricle/ventricular; MI, myocardial infarction; RV, right ventricular; SR, sarcoplasmic reticulum; T-tubule, transverse tubule; T-tubules; TAB, transverse aortic banding; TTpower, strength of regularity of the T-tubule system; WT, wild-type; calcium; calpain; excitation-contraction coupling; heart failure

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JACC Basic Transl Sci Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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