Characteristics of optic neuropathy in Behçet disease.
Neurol Neuroimmunol Neuroinflamm
; 5(5): e490, 2018 Sep.
Article
en En
| MEDLINE
| ID: mdl-30175164
OBJECTIVE: We present the clinical profile, features, and neuroimaging findings of 25 patients with Behçet disease (BD), and optic neuropathy (ON), which has been rarely reported in BD. METHODS: Data from 5 university hospitals were retrospectively reviewed, and patients with BD and ON were evaluated. There were 2 groups: (1) those already diagnosed with BD when ON developed (BDâON group) and (2) those diagnosed with BD during the evaluation of ON (ONâBD group). RESULTS: There were 25 BD patients with ON (13 males). Among these, 13 had ONâBD, and 12 had BDâON. Seventeen patients had unilateral ON, and 7 patients had recurrent ON. BDâON patients were older. Disc edema was seen more in ONâBD than in BDâON patients (10 vs 3). Fourteen patients also had uveitis, 7 with BDâON and 7 with ONâBD. There was other neurologic involvement in 8 patients; in the BDâON group, 4/4 had MS-like disease, in the ONâBD group, 3 had typical parenchymal BD, and 1 had MS-like disease. Twenty of 21 patients received immunosuppressive medications, corticosteroids, or both. Prognosis was favorable in most: vision improved in 20 patients, more often in those receiving combined therapies. CONCLUSION: BD may be diagnosed earlier if it is considered and investigated during the assessment of ON, particularly in high-risk regions. Prognosis of ON related to BD seems to be favorable. Immunosuppressants should be given along with corticosteroids. MS-like presentations should also be kept in mind in patients with BD and ON.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Neurol Neuroimmunol Neuroinflamm
Año:
2018
Tipo del documento:
Article
Pais de publicación:
Estados Unidos