Development of a new doubly-labeled fluorescent ceramide probe for monitoring the metabolism of sphingolipids in living cells.

Wang, Yabin; Kasahara, Junya; Yamagata, Kazuyuki; Nakamura, Hiroyuki; Murayama, Toshihiko; Suzuki, Noriyuki; Nishida, Atsushi

Wang, Yabin; Kasahara, Junya; Yamagata, Kazuyuki; Nakamura, Hiroyuki; Murayama, Toshihiko; Suzuki, Noriyuki; Nishida, Atsushi.

Afiliación

Wang Y; Laboratory of Synthetic Organic Chemistry, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan.
Kasahara J; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan.
Yamagata K; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan; Laboratory of International Scholars in Pharmaceuticals in Systems Biology, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, C
Nakamura H; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan.
Murayama T; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan.
Suzuki N; Laboratory of Toxicology and Environmental Health, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan.
Nishida A; Laboratory of Synthetic Organic Chemistry, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan; Molecular Chirality Research Center, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, Japan. Electronic address: anishida@faculty.chiba-u.jp.

Bioorg Med Chem Lett ; 28(19): 3222-3226, 2018 10 15.

Article en En | MEDLINE | ID: mdl-30149971

Asunto(s)

Ceramidas/metabolismo; Colorantes Fluorescentes/química; Esfingolípidos/metabolismo; Animales; Cromatografía en Capa Delgada; Cricetinae; Fluorescencia

Palabras clave

Ceramide; Florescent probe; KFL5; NBD; Sphingolipids

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esfingolípidos / Ceramidas / Colorantes Fluorescentes Límite: Animals Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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