Chronic exposure to microcystin-leucine-arginine promoted proliferation of prostate epithelial cells resulting in benign prostatic hyperplasia.

Pan, Chun; Chen, Yabing; Xu, Tianchi; Wang, Jing; Li, Dongmei; Han, Xiaodong

Pan, Chun; Chen, Yabing; Xu, Tianchi; Wang, Jing; Li, Dongmei; Han, Xiaodong.

Afiliación

Pan C; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing 210093, China.
Chen Y; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing 210093, China.
Xu T; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing 210093, China.
Wang J; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing 210093, China.
Li D; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing 210093, China.
Han X; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing 210093, China. Electronic address: hanxd@nju.edu.cn

Environ Pollut ; 242(Pt B): 1535-1545, 2018 Nov.

Article en En | MEDLINE | ID: mdl-30145517

Asunto(s)

Proliferación Celular/efectos de los fármacos; Microcistinas/toxicidad; Próstata/efectos de los fármacos; Hiperplasia Prostática/inducido químicamente; Animales; Arginina/química; Exposición a Riesgos Ambientales; Células Epiteliales/efectos de los fármacos; Proteína Forkhead Box M1/metabolismo; Leucina/química; Masculino; Ratones; Ratones Endogámicos BALB C; Microcistinas/química; Próstata/patología; Transducción de Señal/efectos de los fármacos

Palabras clave

Benign prostatic hyperplasia; Forkhead box protein M1; Microcystin-LR; RWPE-1â¯cell

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Próstata / Hiperplasia Prostática / Proliferación Celular / Microcistinas Límite: Animals Idioma: En Revista: Environ Pollut Asunto de la revista: SAUDE AMBIENTAL Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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