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Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach.
Soto, Ramón; Perez-Herran, Esther; Rodriguez, Beatriz; Duma, Bogdan M; Cacho-Izquierdo, Monica; Mendoza-Losana, Alfonso; Lelievre, Joel; Aguirre, David Barros; Ballell, Lluis; Cox, Liam R; Alderwick, Luke J; Besra, Gurdyal S.
Afiliación
  • Soto R; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
  • Perez-Herran E; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain.
  • Rodriguez B; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain.
  • Duma BM; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, UK.
  • Cacho-Izquierdo M; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain.
  • Mendoza-Losana A; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain.
  • Lelievre J; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain.
  • Aguirre DB; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain.
  • Ballell L; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain.
  • Cox LR; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, UK.
  • Alderwick LJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
  • Besra GS; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. g.besra@bham.ac.uk.
Sci Rep ; 8(1): 12664, 2018 08 23.
Article en En | MEDLINE | ID: mdl-30140040
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aspartato-ARNt Ligasa / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Diagnostic_studies Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aspartato-ARNt Ligasa / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Diagnostic_studies Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido