Betulinic acid exerts potent antitumor effects on paclitaxel-resistant human lung carcinoma cells (H460) via G2/M phase cell cycle arrest and induction of mitochondrial apoptosis.

Zhan, Xiao-Kai; Li, Jun-Ling; Zhang, Sen; Xing, Pu-Yuan; Xia, Meng-Fan

Zhan, Xiao-Kai; Li, Jun-Ling; Zhang, Sen; Xing, Pu-Yuan; Xia, Meng-Fan.

Afiliación

Zhan XK; Department of Hematology and Oncology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100043, P.R. China.
Li JL; Department of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China.
Zhang S; Department of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, P.R. China.
Xing PY; Department of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, P.R. China.
Xia MF; Department of Pharmacology, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Material Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, P.R. China.

Oncol Lett ; 16(3): 3628-3634, 2018 Sep.

Article en En | MEDLINE | ID: mdl-30127971

Palabras clave

apoptosis; cell cycle arrest; drug resistance; lung cancer

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Oncol Lett Año: 2018 Tipo del documento: Article Pais de publicación: Grecia

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