The conformation and dynamics of P-glycoprotein in a lipid bilayer investigated by atomic force microscopy.

Sigdel, K P; Wilt, L A; Marsh, B P; Roberts, A G; King, G M

Sigdel, K P; Wilt, L A; Marsh, B P; Roberts, A G; King, G M.

Afiliación

Sigdel KP; Department of Physics and Astronomy, University of Missouri, Columbia, MO 65211, United States.
Wilt LA; Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA 30602, United States.
Marsh BP; Department of Physics and Astronomy, University of Missouri, Columbia, MO 65211, United States.
Roberts AG; Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA 30602, United States. Electronic address: audie@uga.edu.
King GM; Department of Physics and Astronomy, University of Missouri, Columbia, MO 65211, United States; Joint with Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States. Electronic address: kinggm@missouri.edu.

Biochem Pharmacol ; 156: 302-311, 2018 10.

Article en En | MEDLINE | ID: mdl-30121251

Asunto(s)

Miembro 1 de la Subfamilia B de Casetes de Unión a ATP/química; Membrana Dobles de Lípidos/química; Animales; Liposomas; Ratones; Microscopía de Fuerza Atómica; Conformación Proteica

Palabras clave

Atomic force microscopy (AFM); Drug distribution; Membrane-bound protein modeling; Multidrug resistance transporters; Protein conformation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Miembro 1 de la Subfamilia B de Casetes de Unión a ATP / Membrana Dobles de Lípidos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biochem Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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