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Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins.
Ippagunta, Sirish K; Pollock, Julie A; Sharma, Naina; Lin, Wenwei; Chen, Taosheng; Tawaratsumida, Kazuki; High, Anthony A; Min, Jaeki; Chen, Yizhe; Guy, R Kiplin; Redecke, Vanessa; Katzenellenbogen, John A; Häcker, Hans.
Afiliación
  • Ippagunta SK; Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
  • Pollock JA; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Sharma N; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Lin W; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Chen T; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Tawaratsumida K; Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
  • High AA; St. Jude Proteomics Facility, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Min J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Chen Y; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Guy RK; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Redecke V; Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
  • Katzenellenbogen JA; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. hans.haecker@stjude.org jkatzene@illinois.edu.
  • Häcker H; Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. hans.haecker@stjude.org jkatzene@illinois.edu.
Sci Signal ; 11(543)2018 08 14.
Article en En | MEDLINE | ID: mdl-30108181
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperidinas / Pirazoles / Transducción de Señal / Receptores Toll-Like / Bibliotecas de Moléculas Pequeñas Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperidinas / Pirazoles / Transducción de Señal / Receptores Toll-Like / Bibliotecas de Moléculas Pequeñas Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos