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Accelerated magnetic resonance fingerprinting using soft-weighted key-hole (MRF-SOHO).
Cruz, Gastao; Schneider, Torben; Bruijnen, Tom; Gaspar, Andreia S; Botnar, René M; Prieto, Claudia.
Afiliación
  • Cruz G; School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
  • Schneider T; Philips Healthcare, Guilford, United Kingdom.
  • Bruijnen T; Department of Radiotherapy, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Gaspar AS; Institute for Systems and Robotics / Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
  • Botnar RM; School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
  • Prieto C; Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile.
PLoS One ; 13(8): e0201808, 2018.
Article en En | MEDLINE | ID: mdl-30092033
OBJECT: To develop a novel approach for highly accelerated Magnetic Resonance Fingerprinting (MRF) acquisition. MATERIALS AND METHODS: The proposed method combines parallel imaging, soft-gating and key-hole approaches to highly accelerate MRF acquisition. Slowly varying flip angles (FA), commonly used during MRF acquisition, lead to a smooth change in the signal contrast of consecutive time-point images. This assumption enables sharing of high frequency data between different time-points, similar to what is done in some dynamic MR imaging methods such as key-hole. The proposed approach exploits this information using a SOft-weighted key-HOle (MRF-SOHO) reconstruction to achieve high acceleration factors and/or increased resolution without compromising image quality or increasing scan time. MRF-SOHO was validated on a standard T1/T2 phantom and in in-vivo brain acquisitions reconstructing T1, T2 and proton density parametric maps. RESULTS: Accelerated MRF-SOHO using less data per time-point and less time-point images enabled a considerable reduction in scan time (up to 4.6x), while obtaining similar T1 and T2 accuracy and precision when compared to zero-filled MRF reconstruction. For the same number of spokes and time-points, the proposed method yielded an enhanced performance in quantifying parameters than the zero-filled MRF reconstruction, which was verified with 2, 1 and 0.7 (sub-millimetre) resolutions. CONCLUSION: The proposed MRF-SOHO enabled a 4.6x scan time reduction for an in-plane spatial resolution of 2x2 mm2 when compared to zero-filled MRF and enabled sub-millimetric (0.7x0.7 mm2) resolution MRF.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos