Replication stress response in cancer stem cells as a target for chemotherapy.

Manic, Gwenola; Sistigu, Antonella; Corradi, Francesca; Musella, Martina; De Maria, Ruggero; Vitale, Ilio

Manic, Gwenola; Sistigu, Antonella; Corradi, Francesca; Musella, Martina; De Maria, Ruggero; Vitale, Ilio.

Afiliación

Manic G; Department of Research, Advanced Diagnostics and Technological Innovation, IRCCS - Regina Elena National Cancer Institute, Rome, Italy. Electronic address: gwenola.manic@gmail.com.
Sistigu A; Department of Research, Advanced Diagnostics and Technological Innovation, IRCCS - Regina Elena National Cancer Institute, Rome, Italy; Institute of General Pathology, Catholic University and Gemelli Polyclinic, Rome, Italy.
Corradi F; Department of Biology, University of Rome "Tor Vergata", Rome, Italy.
Musella M; Department of Research, Advanced Diagnostics and Technological Innovation, IRCCS - Regina Elena National Cancer Institute, Rome, Italy; Department of Molecular Medicine, University "La Sapienza", Rome, Italy.
De Maria R; Institute of General Pathology, Catholic University and Gemelli Polyclinic, Rome, Italy. Electronic address: ruggero.demaria@unicatt.it.
Vitale I; Department of Research, Advanced Diagnostics and Technological Innovation, IRCCS - Regina Elena National Cancer Institute, Rome, Italy; Department of Biology, University of Rome "Tor Vergata", Rome, Italy. Electronic address: iliovit@gmail.com.

Semin Cancer Biol ; 53: 31-41, 2018 12.

Article en En | MEDLINE | ID: mdl-30081229

Asunto(s)

Replicación del ADN/genética; Neoplasias/genética; Células Madre Neoplásicas/metabolismo; Transducción de Señal/genética; Animales; Antineoplásicos/uso terapéutico; Daño del ADN; Reparación del ADN; Replicación del ADN/efectos de los fármacos; Humanos; Neoplasias/tratamiento farmacológico; Neoplasias/patología; Células Madre Neoplásicas/efectos de los fármacos; Transducción de Señal/efectos de los fármacos

Palabras clave

Aneuploidy; Chromosomal instability; Fork reversal; Replication catastrophe; Tumor-initiating cells

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Transducción de Señal / Replicación del ADN / Neoplasias Límite: Animals / Humans Idioma: En Revista: Semin Cancer Biol Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido

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