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Treatment and survival of rectal cancer patients over the age of 80 years: a EURECCA international comparison.
Claassen, Yvette H M; Vermeer, Nina C A; Iversen, Lene H; van Eycken, Elizabeth; Guren, Marianne G; Mroczkowski, Pawel; Martling, Anna; Codina Cazador, Antonio; Johansson, Robert; Vandendael, Tamara; Wibe, Arne; Moller, Bjorn; Lippert, Hans; Rutten, Harm J T; Portielje, Johanneke E A; Liefers, Gerrit J; Holman, Fabian A; van de Velde, Cornelis J H; Bastiaannet, Esther.
Afiliación
  • Claassen YHM; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
  • Vermeer NCA; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
  • Iversen LH; Department of Surgery, Aarhus University Hospital, Aarhus, Denmark.
  • van Eycken E; Danish Colorectal Cancer Group (DCCG.dk), Copenhagen, Denmark.
  • Guren MG; Belgian Cancer Registry, Brussels, Belgium.
  • Mroczkowski P; Department of Oncology and K.G. Jebsen Colorectal Cancer Research Centre, Oslo University Hospital, Oslo, Norway.
  • Martling A; Institute for Quality Assurance in Operative Medicine Ltd at Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
  • Codina Cazador A; Department for General and Visceral Surgery, Elisabeth Hospital, Kassel, Germany.
  • Johansson R; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Vandendael T; Department of Surgery, Generalitat de Catalunya, Barcelona, Spain.
  • Wibe A; Department of Radiation Science, Oncology, Umeå University, Umeå, Sweden.
  • Moller B; Belgian Cancer Registry, Brussels, Belgium.
  • Lippert H; Institute of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology-NTNU, Trondheim, Norway.
  • Rutten HJT; Cancer Registry of Norway, Oslo, Norway.
  • Portielje JEA; Institute for Quality Assurance in Operative Medicine Ltd at Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
  • Liefers GJ; Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands.
  • Holman FA; GROW: School of Oncology and Developmental Biology, University of Maastricht, Maastricht, The Netherlands.
  • van de Velde CJH; Department of Gerontology & Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
  • Bastiaannet E; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Br J Cancer ; 119(4): 517-522, 2018 08.
Article en En | MEDLINE | ID: mdl-30057408
BACKGROUND: The optimal treatment strategy for older rectal cancer patients remains unclear. The current study aimed to compare treatment and survival of rectal cancer patients aged 80+. METHODS: Patients of ≥80 years diagnosed with rectal cancer between 2001 and 2010 were included. Population-based cohorts from Belgium (BE), Denmark (DK), the Netherlands (NL), Norway (NO) and Sweden (SE) were compared side by side for neighbouring countries on treatment strategy and 5-year relative survival (RS), adjusted for sex and age. Analyses were performed separately for stage I-III patients and stage IV patients. RESULTS: Overall, 19 634 rectal cancer patients were included. For stage I-III patients, 5-year RS varied from 61.7% in BE to 72.3% in SE. Proportion of preoperative radiotherapy ranged between 7.9% in NO and 28.9% in SE. For stage IV patients, 5-year RS differed from 2.8% in NL to 5.6% in BE. Rate of patients undergoing surgery varied from 22.2% in DK to 40.8% in NO. CONCLUSIONS: Substantial variation was observed in the 5-year relative survival between European countries for rectal cancer patients aged 80+, next to a wide variation in treatment, especially in the use of preoperative radiotherapy in stage I-III patients and in the rate of patients undergoing surgery in stage IV patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto / Procedimientos Quirúrgicos del Sistema Digestivo / Radioterapia Adyuvante Límite: Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Br J Cancer Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto / Procedimientos Quirúrgicos del Sistema Digestivo / Radioterapia Adyuvante Límite: Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Br J Cancer Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido