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Vitamin D: And its role in breast cancer.
de La Puente-Yagüe, Miriam; Cuadrado-Cenzual, Maria A; Ciudad-Cabañas, María J; Hernández-Cabria, Marta; Collado-Yurrita, Luis.
Afiliación
  • de La Puente-Yagüe M; Obstetrics and Gynecology, Hospital Clínico Universitario, San Carlos, Madrid, Spain.
  • Cuadrado-Cenzual MA; Laboratory of Medicine, Hospital Clínico Universitario, San Carlos, Madrid, Spain.
  • Ciudad-Cabañas MJ; Department of Medicine, Complutense University, Madrid, Spain.
  • Hernández-Cabria M; Department of Medicine, Complutense University, Madrid, Spain.
  • Collado-Yurrita L; Department of Medicine, Complutense University, Madrid, Spain. Electronic address: lcollado@ucm.es.
Kaohsiung J Med Sci ; 34(8): 423-427, 2018 Aug.
Article en En | MEDLINE | ID: mdl-30041759
Vitamin D is a fat soluble vitamin that plays a role in calcium and phosphorus homeostasis. Recently, extensive research on its extraskeletal actions has linked vitamin D deficiency to an increased risk of infection, diabetes mellitus types 1 and 2, cardiovascular disease, obesity, asthma, inflammatory bowel disease, colon, breast, prostate and ovarian cancer and some neurological diseases. There are various mechanisms by which vitamin D influences the natural history of cancer. These include the role of vitamin D in the induction of apoptosis, stimulation of cell differentiation, anti-inflammatory and antiproliferative effects and inhibition of angiogenesis, invasion and metastasis. The aim of this review is to clarify the true role of vitamin D in the onset of breast cancer and evolution of the disease after treatment. A further aim is to suggest new research directions to identify indications and requirements for vitamin D supplementation in patients with breast cancer.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vitamina D / Neoplasias de la Mama Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Kaohsiung J Med Sci Asunto de la revista: MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: España Pais de publicación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vitamina D / Neoplasias de la Mama Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Kaohsiung J Med Sci Asunto de la revista: MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: España Pais de publicación: China