Chemical Strategies for Half-Life Extension of Biopharmaceuticals: Lipidation and Its Alternatives.
ACS Med Chem Lett
; 9(7): 577-580, 2018 Jul 12.
Article
en En
| MEDLINE
| ID: mdl-30034579
Strategies for half-life extension are often required in the design of new biopharmaceuticals. This Viewpoint focuses on chemical moieties that convey protraction by albumin binding or by self-assembly to form larger structures, with GLP-1 and insulin as examples.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
ACS Med Chem Lett
Año:
2018
Tipo del documento:
Article
País de afiliación:
Dinamarca
Pais de publicación:
Estados Unidos