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Agarose-silver particles films: Effect of calcium ascorbate in nanoparticles synthesis and film properties.
Onofre-Cordeiro, Natália A; Silva, Yago E O; Solidônio, Evelyne G; de Sena, Kêsia X F R; Silva, Wagner E; Santos, Beate S; Aquino, Kátia A S; Lima, Cláudia S A; Yara, Ricardo.
Afiliación
  • Onofre-Cordeiro NA; Department of Biomedical Engineering, Technology and Geosciences Center, Federal University of Pernambuco, Professor Morais Rego Avenue, s/n - Cidade Universitaria, Recife, PE, Brazil.
  • Silva YEO; Department of Biomedical Engineering, Technology and Geosciences Center, Federal University of Pernambuco, Professor Morais Rego Avenue, s/n - Cidade Universitaria, Recife, PE, Brazil.
  • Solidônio EG; Department of Antibiotics, Biosciences Center, Federal University of Pernambuco, Professor Morais Rego Avenue, s/n - Cidade Universitaria, Recife, PE, Brazil; Faculdade Integrada de Pernambuco, Caxangá Avenue, 4477 - Cidade Universitária, Recife - PE, Brazil.
  • de Sena KXFR; Department of Antibiotics, Biosciences Center, Federal University of Pernambuco, Professor Morais Rego Avenue, s/n - Cidade Universitaria, Recife, PE, Brazil.
  • Silva WE; Department of Chemistry, Rural Federal University of Pernambuco, Dom Manoel de Medeiros Avenue, s/n - Dois Irmãos, Recife, PE, Brazil.
  • Santos BS; Department of Pharmaceutical Sciences, Health Sciences Center, Federal University of Pernambuco, Professor Morais Rego Avenue, s/n - Cidade Universitária, Recife, PE, Brazil.
  • Aquino KAS; Postgraduate Program in Energy and Nuclear Technologies, Department of Nuclear Energy, Technology and Geosciences Center, Federal University of Pernambuco, Prof. Luiz Freire Avenue, 1000 - Cidade Universitária, Recife, PE, Brazil.
  • Lima CSA; Department of Biophysics and Radiobiology, Biosciences Center, Federal University of Pernambuco, Professor Morais Rego Avenue, s/n - Cidade Universitária, Recife, PE, Brazil.
  • Yara R; Department of Biomedical Engineering, Technology and Geosciences Center, Federal University of Pernambuco, Professor Morais Rego Avenue, s/n - Cidade Universitaria, Recife, PE, Brazil. Electronic address: ricardo.yara.ufpe@gmail.com.
Int J Biol Macromol ; 119: 701-707, 2018 Nov.
Article en En | MEDLINE | ID: mdl-30031085
New nanoparticles containing biomaterials are emerging as versatile active platforms in a great number of applications, for example, as skin substitutes and therapeutic media. The present study describes the preparation of silver nanoparticles (AgNPs) embedded in agarose films and the impact of calcium ascorbate in the formation of ANPs as well as in the final properties of the films. Colloidal AgNPs were synthetized by two chemical reduction routes: (i) applying calcium ascorbate and NaBH4 and (ii) applying only NaBH4. AgNPs synthetized using NaBH4 showed sizes ranging from 5 to 18 nm while AgNPs were calcium ascorbate was used showed micrometer from 164 to 955 nm size. Films were prepared in three formulations: agarose control film (A1); agarose + AgNPs without calcium ascorbate (A2) and agarose + AgNPs with calcium ascorbate (A3). The characterization of films by SEM and EDS showed agarose agglomerates in A2 and unreacted calcium ascorbate crystals on surface of A3. Thus, the presence of calcium ascorbate influenced the properties of A3 film. In addition, the antimicrobial analysis showed a silver particles release dependence on the film composition and only the A3 presented activity against Staphylococcus aureus. The results found in this study open an important way for development of new biomaterials, economically competitive, and with medical application.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Ascórbico / Sefarosa / Plata / Nanopartículas del Metal / Antibacterianos Idioma: En Revista: Int J Biol Macromol Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Ascórbico / Sefarosa / Plata / Nanopartículas del Metal / Antibacterianos Idioma: En Revista: Int J Biol Macromol Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos