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Accuracy, Ease of Use, Safety, and Acceptability of a 23-µL Conical Cup Blood Transfer Device for Use with Rapid Diagnostic Tests.
Incardona, Sandra; Kyabayinze, Daniel J; Bell, David; Ndawula, Bbale; Kanyago, Marvis C; Mwancha-Kwasa, Magoma C; González, Iveth J.
Afiliación
  • Incardona S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
  • Kyabayinze DJ; National Malaria Control Division, Ministry of Health, Kampala, Uganda.
  • Bell D; Intellectual Ventures, Global Good Fund, Bellevue, Washington.
  • Ndawula B; School of Biomedical Science, Makerere University, Kampala, Uganda.
  • Kanyago MC; Women's Hospital International, Kampala, Uganda.
  • Mwancha-Kwasa MC; Health Research and Development Unit, Ministry of Health, Kiambu, Kenya.
  • González IJ; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Am J Trop Med Hyg ; 99(3): 797-804, 2018 09.
Article en En | MEDLINE | ID: mdl-30014818
Devices to safely transfer fixed amounts of finger prick blood to rapid diagnostic tests (RDTs) pose a significant challenge, especially in non-laboratory settings. Following the success of an "inverted cup device" for transfer of 5 µL blood, a prototype with a conical cup shape was developed for transfer of 20 µL blood, the amount needed for human immunodeficiency virus or human African trypanosomiasis (HAT) RDTs. This study determined the volume of blood transferred by this new blood transfer device (BTD) and compared its ease of use, safety, and acceptability with that of a plastic pipette when used by health workers (HWs) for HAT RDTs in northwestern Uganda. After a half-day training, 48 HWs had used the two BTDs with at least 10 patients. The conical cup BTD effectively transferred a mean of 22.76 µL of blood (standard deviation 3.31 µL). A significantly higher proportion of HWs were able to collect the full amount of blood using the conical cup BTD, as compared with the pipette (92.4% versus 74.2%, P < 0.001). In HW questionnaires, the conical cup BTD scored higher than the pipette in various aspects of ease of use and safety. In addition, HWs preferred the conical cup BTD (79%), indicating that it was easy to handle, made work faster, and increased their confidence in front of the patient. These findings suggest that the design of the conical cup BTD may be adapted for RDTs requiring 20 µL of blood to facilitate safe and accurate blood transfer.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas Serológicas / Recolección de Muestras de Sangre Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Am J Trop Med Hyg Año: 2018 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas Serológicas / Recolección de Muestras de Sangre Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Am J Trop Med Hyg Año: 2018 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos