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Retinopathy of prematurity in the United Kingdom: retreatment rates, visual and structural 1-year outcomes.
Adams, Gillian Gw; Bunce, Catey; Xing, Wen; Butler, Lucilla; Long, Vernon; Reddy, Aravind; Dahlmann-Noor, Annegret H.
Afiliación
  • Adams GG; NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, 162 City Road, London, EC1V 2PD, UK.
  • Bunce C; NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, 162 City Road, London, EC1V 2PD, UK.
  • Xing W; Department of Primary Care and Public Health Sciences, Kings College London, London, SE1 1UL, UK.
  • Butler L; NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, 162 City Road, London, EC1V 2PD, UK.
  • Long V; Birmingham and Midland Eye Centre, Dudley Road, Birmingham, B18 7QH, UK.
  • Reddy A; St James' University Hospital Leeds, Teaching Hospitals, Beckett Street, Leeds, West Yorkshire, LS9 7TF, UK.
  • Dahlmann-Noor AH; Royal Aberdeen Children's Hospital, Westburn Road, Foresterhill, Aberdeen, AB25 2ZG, UK.
Eye (Lond) ; 32(11): 1752-1759, 2018 11.
Article en En | MEDLINE | ID: mdl-30013158
AIMS: To evaluate retreatment rates, visual and anatomical outcomes at 1-year postnatal age in infants treated for retinopathy of prematurity (ROP) METHODS: Longitudinal national surveillance study of infants treated for ROP in the United Kingdom between December 2013 and December 2014, supported by the British Ophthalmic Surveillance Unit. Here we report retreatment rates, anatomical, visual and refractive outcomes at 1-year follow-up. RESULTS: One-year follow-up forms were completed for 168 children of the original cohort of 327 (51.4%). Twenty-two had at least one retreatment: 17/153 right eyes (REs, 11.1%) after initial diode laser, and 5/14 REs (35.7%) after initial injection of anti-vascular endothelial growth factor (VEGF) antibody. Median (interquartile range) RE best-corrected visual acuity was 0.6 (0.4-1.0) (n = 46 REs), and median acuity both eyes open 0.4 (0.3-0.7) logMAR (n = 89). Median spherical equivalent (RE) was 0.44 (-1.3 to 1.3) dioptre (D) (n = 116). Median astigmatism (RE) was 0.5 (0-1.0) D (n = 111), and median anisometropia 0.125 (0-0.75) D (n = 116). Twenty-four children (20.5%) had been prescribed glasses. Sight impairment certification eligibility information was available for 131 children: 11 (8.4%) were eligible to be certified as sight impaired, and 5 (3.8%) as severely sight impaired. CONCLUSIONS: Retreatment rates are in line with previous reports, and appear higher after initial anti-VEGF antibody than after initial diode laser. Refractive outcomes are in line with previous studies, with a trend towards early emmetropia and myopia following diode laser, particularly in more severe ROP.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Retinopatía de la Prematuridad / Retratamiento Tipo de estudio: Observational_studies / Prognostic_studies Límite: Female / Humans / Infant / Male / Newborn País/Región como asunto: Europa Idioma: En Revista: Eye (Lond) Asunto de la revista: OFTALMOLOGIA Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Retinopatía de la Prematuridad / Retratamiento Tipo de estudio: Observational_studies / Prognostic_studies Límite: Female / Humans / Infant / Male / Newborn País/Región como asunto: Europa Idioma: En Revista: Eye (Lond) Asunto de la revista: OFTALMOLOGIA Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido