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Urinary levels of metal elements in the non-smoking general population in Italy: SIVR study 2012-2015.
Aprea, Maria Cristina; Apostoli, Pietro; Bettinelli, Maurizio; Lovreglio, Piero; Negri, Sara; Perbellini, Luigi; Perico, Andrea; Ricossa, Maria Cristina; Salamon, Fabiola; Scapellato, Maria Luisa; Iavicoli, Ivo.
Afiliación
  • Aprea MC; Public Health Laboratory, Local Health Administration South-East Tuscany, Siena, Italy. Electronic address: cristina.aprea@uslsudest.toscana.it.
  • Apostoli P; Department of Medical and Surgical Specialties, Radiological Sciences and Public Health - Section of Public Health and Human Sciences University of Brescia - Spedali Civili di Brescia, Brescia, Italy.
  • Bettinelli M; UNICHIM, Milano, Italy.
  • Lovreglio P; Interdisciplinary Department of Medicine, Section of Occupational Medicine "EC Vigliani", University of Bari Aldo Moro, Bari, Italy.
  • Negri S; Environmental Research Center, ICS MAUGERI SPA SB, Institute of Pavia, IRCCS, Pavia, Italy.
  • Perbellini L; Department of Diagnostics and Public Health, Section of Occupational Medicine, University of Verona, Italy.
  • Perico A; Public Health Laboratory, Local Health Administration Center Tuscany, Firenze, Italy.
  • Ricossa MC; Department of Medical and Surgical Specialties, Radiological Sciences and Public Health - Section of Public Health and Human Sciences University of Brescia - Spedali Civili di Brescia, Brescia, Italy.
  • Salamon F; Department of Cardiology, Thoracic and Vascular Sciences - Public Health Branch, University of Padua, Italy.
  • Scapellato ML; Department of Cardiology, Thoracic and Vascular Sciences - Public Health Branch, University of Padua, Italy.
  • Iavicoli I; Department of Public Health, University of Naples Federico II, Naples, Italy.
Toxicol Lett ; 298: 177-185, 2018 Dec 01.
Article en En | MEDLINE | ID: mdl-30003948
The purpose of this study of the Italian Society of Reference Values (SIVR) was to provide the reference values for metals in the urine of the Italian general population. Thirteen sampling centres situated in the north, centre and south of Italy took part in this project. Each sampling centre selected 20 adult subjects. The sample was made up of 120 male and 140 female non-smokers or smokers who had abandoned the habit at least 5 years previously, aged between 18 and 60 years. Urine samples were obtained from the same subjects in June and again in November of the same year. During collection of these two samples, we administered an ad hoc questionnaire designed to assess factors that might influence exposure and the results of the study such as personal characteristics, occupational or extra-occupational activities, dietary habits, the presence of dental fillings containing amalgam, the frequency and mode of exposure to passive smoking and exhaust gases of motor vehicles (traffic). Therefore, the urinary levels of thirteen trace elements (Be, Cd, Co, Cr, Cu, In, Mn, Ni, Pb, Pt, Sb, Tl and V) were determined by Inductively Coupled Plasma Mass Spectrometry. The concentrations obtained (95th percentile) are in µg/L: 0.034, 0.900, 2.24, 0.600, 24.0, 0.013, 1.53, 4.44, 2.64, 0.022, 0.095, 0.759 and 0.855 for Be, Cd, Co, Cr, Cu, In, Mn, Ni, Pb, Pt, Sb, Tl and V, respectively. Further studies with a larger number of subjects are needed in order to continue the biomonitoring of the Italian general population and to monitor the modified levels over time.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metales Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Toxicol Lett Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metales Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Toxicol Lett Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos