Anti-neuroinflammatory effects of galangin in LPS-stimulated BV-2 microglia through regulation of IL-1ß production and the NF-&#954;B signaling pathways.

Kim, Mi Eun; Park, Pu Reum; Na, Ju Yong; Jung, Inae; Cho, Jun Hwi; Lee, Jun Sik

Anti-neuroinflammatory effects of galangin in LPS-stimulated BV-2 microglia through regulation of IL-1ß production and the NF-κB signaling pathways.

Kim, Mi Eun; Park, Pu Reum; Na, Ju Yong; Jung, Inae; Cho, Jun Hwi; Lee, Jun Sik.

Afiliación

Kim ME; Department of Life Science, BK21-plus Research Team for Bioactive Control Technology, College of Natural Sciences, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea.
Park PR; Department of Life Science, BK21-plus Research Team for Bioactive Control Technology, College of Natural Sciences, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea.
Na JY; Department of Life Science, BK21-plus Research Team for Bioactive Control Technology, College of Natural Sciences, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea.
Jung I; Department of Life Science, BK21-plus Research Team for Bioactive Control Technology, College of Natural Sciences, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea.
Cho JH; Department of Life Science, BK21-plus Research Team for Bioactive Control Technology, College of Natural Sciences, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea.
Lee JS; Department of Life Science, BK21-plus Research Team for Bioactive Control Technology, College of Natural Sciences, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea. junsiklee@chosun.ac.kr.

Mol Cell Biochem ; 451(1-2): 145-153, 2019 Jan.

Article en En | MEDLINE | ID: mdl-29995265

Asunto(s)

Antiinflamatorios/farmacología; Flavonoides/farmacología; Inflamación/tratamiento farmacológico; Interleucina-1beta/metabolismo; Lipopolisacáridos/farmacología; Microglía/efectos de los fármacos; Inhibidor NF-kappaB alfa/metabolismo; Animales; Citocinas/metabolismo; Regulación de la Expresión Génica/efectos de los fármacos; Inflamación/inmunología; Inflamación/metabolismo; Ratones; Microglía/inmunología; Microglía/metabolismo; Mutágenos/farmacología; Óxido Nítrico/metabolismo; Fosforilación; Transducción de Señal

Palabras clave

BV-2 microglial cells; Galangin; IL-1ß production; Neuroinflammation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavonoides / Lipopolisacáridos / Microglía / Interleucina-1beta / Inhibidor NF-kappaB alfa / Inflamación / Antiinflamatorios Límite: Animals Idioma: En Revista: Mol Cell Biochem Año: 2019 Tipo del documento: Article Pais de publicación: Países Bajos

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