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Harnessing synthetic lethality to predict the response to cancer treatment.
Lee, Joo Sang; Das, Avinash; Jerby-Arnon, Livnat; Arafeh, Rand; Auslander, Noam; Davidson, Matthew; McGarry, Lynn; James, Daniel; Amzallag, Arnaud; Park, Seung Gu; Cheng, Kuoyuan; Robinson, Welles; Atias, Dikla; Stossel, Chani; Buzhor, Ella; Stein, Gidi; Waterfall, Joshua J; Meltzer, Paul S; Golan, Talia; Hannenhalli, Sridhar; Gottlieb, Eyal; Benes, Cyril H; Samuels, Yardena; Shanks, Emma; Ruppin, Eytan.
Afiliación
  • Lee JS; Center for Bioinformatics and Computational Biology, University of Maryland Institute of Advanced Computer Science (UMIACS) & Department of Computer Science, University of Maryland, College Park, MD, 20742, USA.
  • Das A; Cancer Data Science Lab, National Cancer Institute, National Institute of Health, Bethesda, MD, 20892, USA.
  • Jerby-Arnon L; Center for Bioinformatics and Computational Biology, University of Maryland Institute of Advanced Computer Science (UMIACS) & Department of Computer Science, University of Maryland, College Park, MD, 20742, USA.
  • Arafeh R; The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, 6997801, Israel.
  • Auslander N; Department of Molecular Cell Biology, Weizmann Institute, Rehovot, 7610001, Israel.
  • Davidson M; Center for Bioinformatics and Computational Biology, University of Maryland Institute of Advanced Computer Science (UMIACS) & Department of Computer Science, University of Maryland, College Park, MD, 20742, USA.
  • McGarry L; Cancer Data Science Lab, National Cancer Institute, National Institute of Health, Bethesda, MD, 20892, USA.
  • James D; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow, G61 1BD, Scotland, UK.
  • Amzallag A; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow, G61 1BD, Scotland, UK.
  • Park SG; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow, G61 1BD, Scotland, UK.
  • Cheng K; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA, 02129, USA.
  • Robinson W; Harvard Medical School, Boston, MA, 02114, USA.
  • Atias D; PatientsLikeMe, 160 Second Street, Cambridge, MA, 02142, USA.
  • Stossel C; Center for Bioinformatics and Computational Biology, University of Maryland Institute of Advanced Computer Science (UMIACS) & Department of Computer Science, University of Maryland, College Park, MD, 20742, USA.
  • Buzhor E; Center for Bioinformatics and Computational Biology, University of Maryland Institute of Advanced Computer Science (UMIACS) & Department of Computer Science, University of Maryland, College Park, MD, 20742, USA.
  • Stein G; Cancer Data Science Lab, National Cancer Institute, National Institute of Health, Bethesda, MD, 20892, USA.
  • Waterfall JJ; Center for Bioinformatics and Computational Biology, University of Maryland Institute of Advanced Computer Science (UMIACS) & Department of Computer Science, University of Maryland, College Park, MD, 20742, USA.
  • Meltzer PS; Cancer Data Science Lab, National Cancer Institute, National Institute of Health, Bethesda, MD, 20892, USA.
  • Golan T; Division of Oncology, Sheba Medical Center Tel Hashomer, Ramat-Gan, 5262100, Israel.
  • Hannenhalli S; Division of Oncology, Sheba Medical Center Tel Hashomer, Ramat-Gan, 5262100, Israel.
  • Gottlieb E; Division of Oncology, Sheba Medical Center Tel Hashomer, Ramat-Gan, 5262100, Israel.
  • Benes CH; The Sackler School of Medicine, Tel Aviv University, Tel Aviv, 6997801, Israel.
  • Samuels Y; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Shanks E; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Ruppin E; Division of Oncology, Sheba Medical Center Tel Hashomer, Ramat-Gan, 5262100, Israel.
Nat Commun ; 9(1): 2546, 2018 06 29.
Article en En | MEDLINE | ID: mdl-29959327

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Medicina de Precisión / Ensayos Analíticos de Alto Rendimiento / Mutaciones Letales Sintéticas / Neoplasias / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Medicina de Precisión / Ensayos Analíticos de Alto Rendimiento / Mutaciones Letales Sintéticas / Neoplasias / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido