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Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours.
Garcia-Bermudez, Javier; Baudrier, Lou; La, Konnor; Zhu, Xiphias Ge; Fidelin, Justine; Sviderskiy, Vladislav O; Papagiannakopoulos, Thales; Molina, Henrik; Snuderl, Matija; Lewis, Caroline A; Possemato, Richard L; Birsoy, Kivanç.
Afiliación
  • Garcia-Bermudez J; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Baudrier L; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • La K; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Zhu XG; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Fidelin J; Proteomics Resource Center, The Rockefeller University, New York, NY, USA.
  • Sviderskiy VO; Department of Pathology, New York University School of Medicine, New York, NY, USA.
  • Papagiannakopoulos T; Department of Pathology, New York University School of Medicine, New York, NY, USA.
  • Molina H; Proteomics Resource Center, The Rockefeller University, New York, NY, USA.
  • Snuderl M; Department of Pathology, New York University School of Medicine, New York, NY, USA.
  • Lewis CA; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
  • Possemato RL; Department of Pathology, New York University School of Medicine, New York, NY, USA.
  • Birsoy K; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA. kbirsoy@rockefeller.edu.
Nat Cell Biol ; 20(7): 775-781, 2018 07.
Article en En | MEDLINE | ID: mdl-29941933

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Aspártico / Proliferación Celular / Metabolismo Energético / Microambiente Tumoral / Hipoxia Tumoral / Neoplasias Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Humans / Middle aged Idioma: En Revista: Nat Cell Biol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Aspártico / Proliferación Celular / Metabolismo Energético / Microambiente Tumoral / Hipoxia Tumoral / Neoplasias Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Humans / Middle aged Idioma: En Revista: Nat Cell Biol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido