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Spectral Domain Optical Coherence Tomography Allows the Unification of Clinical Decision Making for the Evaluation of Choroidal Neovascularization Activity.
Volz, Cornelia; Grassmann, Felix; Greslechner, Roman; Märker, David Arthur; Peters, Patrick; Helbig, Horst; Gamulescu, Maria-Andreea.
Afiliación
  • Volz C; Department of Ophthalmology, University Hospital Regensburg, Regensburg, GermanyCornelia.Volz@klinik.uni-regensburg.de.
  • Grassmann F; Institute of Human Genetics, University of Regensburg, Regensburg, Germany.
  • Greslechner R; Department of Ophthalmology, University Hospital Regensburg, Regensburg, Germany.
  • Märker DA; Department of Ophthalmology, University Hospital Regensburg, Regensburg, Germany.
  • Peters P; Department of Ophthalmology, University Hospital Regensburg, Regensburg, Germany.
  • Helbig H; Department of Ophthalmology, University Hospital Regensburg, Regensburg, Germany.
  • Gamulescu MA; Department of Ophthalmology, University Hospital Regensburg, Regensburg, Germany.
Ophthalmologica ; 241(1): 32-37, 2019.
Article en En | MEDLINE | ID: mdl-29929185
PURPOSE: This prospective observational clinical study investigated the benefits of spectral domain optical coherence tomography for specialists and residents in the management of neovascular age-related macular degeneration (AMD). PROCEDURES: The study involved 49 eyes of 44 patients. Patients were advised to present for reevaluation 4 weeks after the administration of the loading dose of vascular endothelial growth factor (VEGF)-inhibitors (3 intravitreal injections every 4 weeks after diagnosis). They were examined by residents (3-4 years' experience in ophthalmology) and specialists (> 5 years' experience). Each examiner evaluated the clinical situation and the spectral domain optical coherence tomography (SD-OCT) scan. After each evaluation, the examiners independently stated if further anti-VEGF treatment was recommended. The "true outcome" was defined as the specialist decision based on clinical evaluation and SD-OCT. RESULTS: Specialists and residents did not significantly differ in their accuracy in deciding on the correct treatment (p = 0.705 and p = 1), with or without the aid of SD-OCT. Both groups benefited from using SD-OCT to support their recommendations (p = 0.001 and p = 0.0002) and achieved a similar level of accuracy (p = 1 for difference). CONCLUSIONS: Residents benefited more than specialists by using SD-OCT to substantiate their recommendation on how to manage exudative AMD after the administration of the loading dose.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Angiografía con Fluoresceína / Coroides / Neovascularización Coroidal / Tomografía de Coherencia Óptica / Toma de Decisiones Clínicas Tipo de estudio: Guideline / Observational_studies / Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ophthalmologica Año: 2019 Tipo del documento: Article Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Angiografía con Fluoresceína / Coroides / Neovascularización Coroidal / Tomografía de Coherencia Óptica / Toma de Decisiones Clínicas Tipo de estudio: Guideline / Observational_studies / Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ophthalmologica Año: 2019 Tipo del documento: Article Pais de publicación: Suiza