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Altered exocrine function can drive adipose wasting in early pancreatic cancer.
Danai, Laura V; Babic, Ana; Rosenthal, Michael H; Dennstedt, Emily A; Muir, Alexander; Lien, Evan C; Mayers, Jared R; Tai, Karen; Lau, Allison N; Jones-Sali, Paul; Prado, Carla M; Petersen, Gloria M; Takahashi, Naoki; Sugimoto, Motokazu; Yeh, Jen Jen; Lopez, Nicole; Bardeesy, Nabeel; Fernandez-Del Castillo, Carlos; Liss, Andrew S; Koong, Albert C; Bui, Justin; Yuan, Chen; Welch, Marisa W; Brais, Lauren K; Kulke, Matthew H; Dennis, Courtney; Clish, Clary B; Wolpin, Brian M; Vander Heiden, Matthew G.
Afiliación
  • Danai LV; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Babic A; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Rosenthal MH; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dennstedt EA; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Muir A; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Lien EC; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Mayers JR; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Tai K; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Lau AN; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Jones-Sali P; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Prado CM; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
  • Petersen GM; Mayo Clinic, Rochester, MN, USA.
  • Takahashi N; Mayo Clinic, Rochester, MN, USA.
  • Sugimoto M; Mayo Clinic, Rochester, MN, USA.
  • Yeh JJ; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Lopez N; University of California San Diego School of Medicine, La Jolla, CA, USA.
  • Bardeesy N; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
  • Fernandez-Del Castillo C; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
  • Liss AS; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
  • Koong AC; MD Anderson, Department of Radiation Oncology, Houston, TX, USA.
  • Bui J; Stanford Cancer Institute, Stanford, CA, USA.
  • Yuan C; Stanford Cancer Institute, Stanford, CA, USA.
  • Welch MW; David Geffen School of Medicine at University of California, Los Angeles, CA, USA.
  • Brais LK; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Kulke MH; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dennis C; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Clish CB; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wolpin BM; Section of Hematology/Oncology, Boston University and Boston Medical Center, Boston, MA, USA.
  • Vander Heiden MG; Broad Institute of MIT and Harvard University, Cambridge, MA, USA.
Nature ; 558(7711): 600-604, 2018 06.
Article en En | MEDLINE | ID: mdl-29925948
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Pancreática Exocrina / Neoplasias Pancreáticas / Tejido Adiposo Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Límite: Animals Idioma: En Revista: Nature Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Pancreática Exocrina / Neoplasias Pancreáticas / Tejido Adiposo Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Límite: Animals Idioma: En Revista: Nature Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido