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Development of Mobile Laboratory for Viral Hemorrhagic Fever Detection in Africa.
Weidmann, Manfred; Faye, Ousmane; Faye, Oumar; Abd El Wahed, Ahmed; Patel, Pranav; Batejat, Christophe; Manugerra, Jean Claude; Adjami, Aimee; Niedrig, Matthias; Hufert, Frank T; Sall, Amadou A.
Afiliación
  • Weidmann M; Institute of Aquaculture, University of Stirling, Scotland, United Kingdom.
  • Faye O; Arbovirus Unit, Pasteur Institute, Dakar, Senegal.
  • Faye O; Arbovirus Unit, Pasteur Institute, Dakar, Senegal.
  • Abd El Wahed A; Unit of Infection Models, German Primate Center, Goettingen, Germany.
  • Patel P; Division of Microbiology and Animal Hygiene, University of Goettingen, Germany.
  • Batejat C; TIB Molbiol Syntheselabor GmbH, Berlin, Germany.
  • Manugerra JC; Laboratory for Urgent Response to Biological Threats (CIBU), Environment and Infectious Risks Unit, Institut Pasteur, Paris, France.
  • Adjami A; Laboratory for Urgent Response to Biological Threats (CIBU), Environment and Infectious Risks Unit, Institut Pasteur, Paris, France.
  • Niedrig M; Multi Disease Surveillance Centre WHO, Ougadougou, Burkina Faso.
  • Hufert FT; Robert Koch Institute, Berlin, Germany.
  • Sall AA; Institute of Microbiology and Virology, Brandenburg Medical School Fontane (and Member of the Faculty of Environment and Natural Sciences of B-TU Senftenberg site), Senftenberg, Brandenburg, Germany.
J Infect Dis ; 218(10): 1622-1630, 2018 10 05.
Article en En | MEDLINE | ID: mdl-29917112
Background: A mobile laboratory transportable on commercial flights was developed to enable local response to viral hemorrhagic fever outbreaks. Methods: The development progressed from use of mobile real-time reverse-transcription polymerase chain reaction to mobile real-time recombinase polymerase amplification. In this study, we describe various stages of the mobile laboratory development. Results: A brief overview of mobile laboratory deployments, which culminated in the first on-site detection of Ebola virus disease (EVD) in March 2014, and their successful use in a campaign to roll back EVD cases in Conakry in the West Africa Ebola virus outbreak are described. Conclusions: The developed mobile laboratory successfully enabled local teams to perform rapid disgnostic testing for viral hemorrhagic fever.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistemas de Atención de Punto / Fiebre Hemorrágica Ebola / Laboratorios / Unidades Móviles de Salud Tipo de estudio: Diagnostic_studies Límite: Humans País/Región como asunto: Africa Idioma: En Revista: J Infect Dis Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistemas de Atención de Punto / Fiebre Hemorrágica Ebola / Laboratorios / Unidades Móviles de Salud Tipo de estudio: Diagnostic_studies Límite: Humans País/Región como asunto: Africa Idioma: En Revista: J Infect Dis Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos