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A human MUTYH variant linking colonic polyposis to redox degradation of the [4Fe4S]2+ cluster.
McDonnell, Kevin J; Chemler, Joseph A; Bartels, Phillip L; O'Brien, Elizabeth; Marvin, Monica L; Ortega, Janice; Stern, Ralph H; Raskin, Leon; Li, Guo-Min; Sherman, David H; Barton, Jacqueline K; Gruber, Stephen B.
Afiliación
  • McDonnell KJ; University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
  • Chemler JA; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
  • Bartels PL; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.
  • O'Brien E; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.
  • Marvin ML; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Ortega J; Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Stern RH; Division of Molecular Medicine and Genetics, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
  • Raskin L; Amgen Inc., Thousand Oaks, CA, USA.
  • Li GM; Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Sherman DH; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. davidhs@umich.edu.
  • Barton JK; Departments of Medicinal Chemistry, Chemistry and Microbiology & Immunology, University of Michigan, Ann Arbor, MI, USA. davidhs@umich.edu.
  • Gruber SB; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA. jkbarton@caltech.edu.
Nat Chem ; 10(8): 873-880, 2018 08.
Article en En | MEDLINE | ID: mdl-29915346

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Colon / Poliposis Adenomatosa del Colon / ADN Glicosilasas / Proteínas Hierro-Azufre Límite: Humans Idioma: En Revista: Nat Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Colon / Poliposis Adenomatosa del Colon / ADN Glicosilasas / Proteínas Hierro-Azufre Límite: Humans Idioma: En Revista: Nat Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido