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Lipid metabolism and carcinogenesis, cancer development.
Long, Jia; Zhang, Chan-Juan; Zhu, Neng; Du, Ke; Yin, Yu-Fang; Tan, Xi; Liao, Duan-Fang; Qin, Li.
Afiliación
  • Long J; School of Pharmacy, Hunan University of Chinese Medicine Changsha, Hunan, China.
  • Zhang CJ; School of Pharmacy, Hunan University of Chinese Medicine Changsha, Hunan, China.
  • Zhu N; The First Affiliated Hospital, Hunan University of Chinese Medicine Changsha, Hunan, China.
  • Du K; School of Pharmacy, Hunan University of Chinese Medicine Changsha, Hunan, China.
  • Yin YF; Department of Neuroscience and Pharmacology, School of Medicine, Southern Illinois University Springfield, Illinois, United States.
  • Tan X; Department of Biochemistry & Molecular Biology, University of Calgary Calgary, Alberta, Canada.
  • Liao DF; School of Pharmacy, Hunan University of Chinese Medicine Changsha, Hunan, China.
  • Qin L; Division of Stem Cell Regulation and Application, Key Lab for Quality Evaluation of Bulk Herbs of Hunan Province, Hunan University of Chinese Medicine Changsha, Hunan Province, China.
Am J Cancer Res ; 8(5): 778-791, 2018.
Article en En | MEDLINE | ID: mdl-29888102
The disorder of lipid metabolism is pathologically linked to hyperlipidemia, lipid storage disease, obesity and other related diseases. Intriguingly, recent studies have revealed that lipid metabolism disorders play an important role in carcinogenesis and development as well, since they cause abnormal expression of various genes, proteins, and dysregulation of cytokines and signaling pathways. More importantly, lipid-lowering drugs and anti-lipid per-oxidation treatment have been showing their advantages in clinic, in comparison with other anti-cancer drugs with high toxicity. Thus, further elucidation of molecular mechanism between lipid metabolism and cancer is essential in developing novel diagnostic biomarkers and therapeutic targets of human cancers.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Am J Cancer Res Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Am J Cancer Res Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos