Long-term toxicity, pharmacokinetics and immune effects of a recombinant adenovirus vaccine expressing human papillomavirus 16 E6 and E7 proteins (HPV16 E6E7-Ad5 Vac) in primates.

Wu, Jie; Chen, Gang; Zhuang, Fang-Cheng; Gao, Meng; Wu, Chuan-Dong; He, Zhan-Long; Jiang, Yun-Shui; Li, Jian-Bo; Bao, Jia-Yuan; Mao, Zi-An

Wu, Jie; Chen, Gang; Zhuang, Fang-Cheng; Gao, Meng; Wu, Chuan-Dong; He, Zhan-Long; Jiang, Yun-Shui; Li, Jian-Bo; Bao, Jia-Yuan; Mao, Zi-An.

Afiliación

Wu J; Institute of Viral Diseases, Zhejiang Academy of Medical Sciences Hangzhou 310013, Zhejiang, P. R. China.
Chen G; Institute of Viral Diseases, Zhejiang Academy of Medical Sciences Hangzhou 310013, Zhejiang, P. R. China.
Zhuang FC; Institute of Viral Diseases, Zhejiang Academy of Medical Sciences Hangzhou 310013, Zhejiang, P. R. China.
Gao M; Institute of Viral Diseases, Zhejiang Academy of Medical Sciences Hangzhou 310013, Zhejiang, P. R. China.
Wu CD; JOINN Laboratories, Inc. Suzhou 215000, Jiangsu, P. R. China.
He ZL; Institute of Medical Biology, Chinese Academy of Medical Sciences Kunming 650100, Yunnan, P. R. China.
Jiang YS; Institute of Viral Diseases, Zhejiang Academy of Medical Sciences Hangzhou 310013, Zhejiang, P. R. China.
Li JB; Institute of Viral Diseases, Zhejiang Academy of Medical Sciences Hangzhou 310013, Zhejiang, P. R. China.
Bao JY; Zhejiang Biotech Co., Ltd. Hangzhou 310053, Zhejiang, P. R. China.
Mao ZA; Zhejiang Biotech Co., Ltd. Hangzhou 310053, Zhejiang, P. R. China.

Am J Transl Res ; 10(5): 1539-1551, 2018.

Article en En | MEDLINE | ID: mdl-29887967

Palabras clave

HPV16; adenovirus vector; immune responses; long-term toxicity; pharmacokinetics; primate

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Am J Transl Res Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos

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