Canine distemper virus active infection in order Pilosa, family Myrmecophagidae, species Tamandua tetradactyla.
Vet Microbiol
; 220: 7-11, 2018 Jul.
Article
en En
| MEDLINE
| ID: mdl-29885804
Canine distemper virus (CDV) is a highly contagious disease pathogen which causes disease in the domestic dog and species classified in the Canidae, Procyonidae, Mustelidae, Hyaenidae, Ursidae, Viveridae, Felidae, Tayassuidae, and Cercopithecidae families. A combined strategy that involved the direct sequencing of amplicons from genes coding for nucleocapsid, large polymerase, and hemagglutinin proteins of CDV, as well as the pathological findings and the immunohistochemical detection of viral nucleocapsid protein in diverse tissues, confirmed the participation of CDV in the development of a neurological disease in a southern tamandua (Tamandua tetradactyla) from Midwestern Brazil. Phylogenetic analysis based on the hemagglutinin gene sequences revealed that the strain from this study grouped with isolates from the Europe 1/South America 1 lineage. The specific polymorphisms at the SLAM receptor-binding site of the hemagglutinin gene, previously linked to disease emergence in novel hosts, were not detected in this genome. These findings represent the first description of CDV-induced infection in the Tamandua tetradactyla and extend the distribution of this infection to include members of the family Myrmecophagidae, order Pilosa.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Moquillo
/
Virus del Moquillo Canino
/
Xenarthra
/
Hemaglutininas Virales
Límite:
Animals
País/Región como asunto:
America do sul
/
Brasil
/
Europa
Idioma:
En
Revista:
Vet Microbiol
Año:
2018
Tipo del documento:
Article
Pais de publicación:
Países Bajos